EMD-23094
Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to one copy of domain-swapped antibody 2G12
EMD-23094
Single-particle3.2 Å
Deposition: 10/12/2020Map released: 30/12/2020
Last modified: 09/06/2021
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Homo sapiens,
Severe acute respiratory syndrome-related coronavirus
Sample: Severe acute respiratory syndrome-related coronavirus spike glycoprotein in complex with domain-swapped antibody 2G12
Fitted models: 7l02
Deposition Authors: Manne K, Henderson R, Acharya P
Sample: Severe acute respiratory syndrome-related coronavirus spike glycoprotein in complex with domain-swapped antibody 2G12
Fitted models: 7l02
Deposition Authors: Manne K, Henderson R, Acharya P
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Williams WB,
Meyerhoff RR 
,
Edwards RJ ,
Li H,
Manne K ,
Nicely NI ,
Henderson R,
Zhou Y ,
Janowska K,
Mansouri K ,
Gobeil S,
Evangelous T,
Hora B,
Berry M,
Abuahmad AY,
Sprenz J,
Deyton M,
Stalls V ,
Kopp M,
Hsu AL,
Borgnia MJ,
Stewart-Jones GBE,
Lee MS,
Bronkema N,
Moody MA,
Wiehe K,
Bradley T,
Alam SM,
Parks RJ,
Foulger A,
Oguin T ,
Sempowski GD ,
Bonsignori M,
LaBranche CC,
Montefiori DC,
Seaman M,
Santra S,
Perfect J,
Francica JR,
Lynn GM,
Aussedat B,
Walkowicz WE,
Laga R,
Kelsoe G ,
Saunders KO,
Fera D,
Kwong PD,
Seder RA,
Bartesaghi A,
Shaw GM,
Acharya P ,
Haynes BF
(2021) Cell , 184 , 2955
,
Edwards RJ ,
Li H,
Manne K ,
Nicely NI ,
Henderson R,
Zhou Y ,
Janowska K,
Mansouri K ,
Gobeil S,
Evangelous T,
Hora B,
Berry M,
Abuahmad AY,
Sprenz J,
Deyton M,
Stalls V ,
Kopp M,
Hsu AL,
Borgnia MJ,
Stewart-Jones GBE,
Lee MS,
Bronkema N,
Moody MA,
Wiehe K,
Bradley T,
Alam SM,
Parks RJ,
Foulger A,
Oguin T ,
Sempowski GD ,
Bonsignori M,
LaBranche CC,
Montefiori DC,
Seaman M,
Santra S,
Perfect J,
Francica JR,
Lynn GM,
Aussedat B,
Walkowicz WE,
Laga R,
Kelsoe G ,
Saunders KO,
Fera D,
Kwong PD,
Seder RA,
Bartesaghi A,
Shaw GM,
Acharya P ,
Haynes BF
(2021) Cell , 184 , 2955