EMD-23687

Helical reconstruction
3.9 Å
EMD-23687
3D View Gallery
Deposition: 25/03/2021
Map released: 22/09/2021
Last modified: 22/09/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-23687
Download
3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7m62 summary report (pdf.gz) Map and 7m62 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils seeded by patient extracted fibrils, polymorph 2

EMD-23687

Helical reconstruction
3.9 Å
EMD-23687
3D View Gallery
Deposition: 25/03/2021
Map released: 22/09/2021
Last modified: 22/09/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: hIAPP fibril
Fitted models: 7m62

Deposition Authors: Cao Q, Boyer DR, Sawaya MR, Eisenberg DS
Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores
Cao Q, Boyer DR, Sawaya MR, Abskharon R, Saelices L, Nguyen BA, Lu J, Murray KA, Kandeel F, Eisenberg DS
(2021) Nat. Struct. Mol. Biol. , 28 , 724 - 730
DOI: doi:10.1038/s41594-021-00646-x
ISSN: 1545-9985