EMD-25427

Single-particle
3.14 Å
EMD-25427
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Deposition: 12/11/2021
Map released: 31/05/2023
Last modified: 25/10/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-25427
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7stf summary report (pdf.gz) Map and 7stf FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of KRAS G12V/HLA-A*03:01 in complex with antibody fragment V2

EMD-25427

Single-particle
3.14 Å
EMD-25427
3D View Gallery
Deposition: 12/11/2021
Map released: 31/05/2023
Last modified: 25/10/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Ternary complex of antibody-fragment V2 with KRAS G12V/HLA-A*03:01
Fitted models: 7stf

Deposition Authors: Wright KM, Gabelli SB
Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen.
Wright KM, DiNapoli SR , Miller MS , Aitana Azurmendi P, Zhao X, Yu Z, Chakrabarti M , Shi W, Douglass J, Hwang MS, Hsiue EH, Mog BJ , Pearlman AH , Paul S , Konig MF , Pardoll DM, Bettegowda C , Papadopoulos N , Kinzler KW, Vogelstein B , Zhou S , Gabelli SB
(2023) Nat Commun , 14 , 5063 - 5063
PUBMED: 37604828
DOI: doi:10.1038/s41467-023-40821-w
ISSN: 2041-1723