EMD-27103

Single-particle
3.14 Å
EMD-27103
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Deposition: 25/05/2022
Map released: 31/05/2023
Last modified: 08/11/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-27103
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8czz summary report (pdf.gz) Map and 8czz FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer with LMHS mutations in complex with Temsavir, 8ANC195, and 10-1074

EMD-27103

Single-particle
3.14 Å
EMD-27103
3D View Gallery
Deposition: 25/05/2022
Map released: 31/05/2023
Last modified: 08/11/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens, Human immunodeficiency virus 1, Severe acute respiratory syndrome coronavirus 2
Sample: Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer with LMHS mutations in complex with Temsavir, 8ANC195, and 10-1074
Fitted models: 8czz

Deposition Authors: Chen Y , Pozharski E, Tolbert W, Pazgier M
Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.
Prevost J, Chen Y , Zhou F, Tolbert WD , Gasser R , Medjahed H, Nayrac M , Nguyen DN, Gottumukkala S, Hessell AJ , Rao VB , Pozharski E, Huang RK, Matthies D , Finzi A, Pazgier M
(2023) Nat Commun , 14 , 6710 - 6710
PUBMED: 37872202
DOI: doi:10.1038/s41467-023-42500-2
ISSN: 2041-1723