EMD-27238

Single-particle
3.4 Å
EMD-27238
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Deposition: 07/06/2022
Map released: 20/07/2022
Last modified: 12/06/2024
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Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-27238
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Cereblon-DDB1 in the Apo form with DDB1 in the twisted conformation

EMD-27238

Single-particle
3.4 Å
EMD-27238
3D View Gallery
Deposition: 07/06/2022
Map released: 20/07/2022
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Cereblon~DDB1 in the Apo form with DDB1 in Twisted conformation
Fitted models: 8d7y

Deposition Authors: Watson ER , Lander GC
Molecular glue CELMoD compounds are regulators of cereblon conformation.
Watson ER , Novick S , Matyskiela ME, Chamberlain PP, H de la Pena A , Zhu J , Tran E, Griffin PR , Wertz IE, Lander GC
(2022) Science , 378 , 549 - 553
PUBMED: 36378961
DOI: doi:10.1126/science.add7574
ISSN: 1095-9203
ASTM: SCIEAS