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EMD-40748

Single-particle
2.72 Å
EMD-40748
3D View Gallery
Deposition: 08/05/2023
Map released: 06/09/2023
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-40748
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8ss9 summary report (pdf.gz) Map and 8ss9 FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state)

EMD-40748

Single-particle
2.72 Å
EMD-40748
3D View Gallery
Deposition: 08/05/2023
Map released: 06/09/2023
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Rattus norvegicus
Sample: GluA2-TARP gamma5
Fitted models: 8ss9

Deposition Authors: Gangwar SP , Yen LY , Yelshanskaya MV , Sobolevsky AI
Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Gangwar SP , Yen LY , Yelshanskaya MV , Korman A , Jones DR , Sobolevsky AI
(2023) Nat Struct Mol Biol , 30 , 1481 - 1494
PUBMED: 37653241
DOI: doi:10.1038/s41594-023-01080-x
ISSN: 1545-9985