EMD-7459
Cryo-EM structure at 3.8 A resolution of vaccine-elicited antibody vFP20.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122
EMD-7459
Single-particle3.8 Å
Deposition: 08/02/2018Map released: 16/05/2018
Last modified: 29/07/2020
Sample Organism:
Homo sapiens,
Human immunodeficiency virus 1
Sample: vFP20.01-BG505 DS-SOSIP-VRC03-PGT122
Fitted models: 6cde
Deposition Authors: Acharya P, Carragher B, Potter CS, Kwong PD
Sample: vFP20.01-BG505 DS-SOSIP-VRC03-PGT122
Fitted models: 6cde
Deposition Authors: Acharya P, Carragher B, Potter CS, Kwong PD
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Xu K,
Acharya P 
,
Kong R,
Cheng C,
Chuang GY,
Liu K ,
Louder MK ,
O'Dell S,
Rawi R,
Sastry M,
Shen CH,
Zhang B,
Zhou T,
Asokan M ,
Bailer RT,
Chambers M,
Chen X,
Choi CW,
Dandey VP,
Doria-Rose NA,
Druz A,
Eng ET ,
Farney SK,
Foulds KE,
Geng H,
Georgiev IS,
Gorman J ,
Hill KR,
Jafari AJ,
Kwon YD,
Lai YT ,
Lemmin T ,
McKee K,
Ohr TY,
Ou L,
Peng D,
Rowshan AP,
Sheng Z ,
Todd JP,
Tsybovsky Y,
Viox EG,
Wang Y,
Wei H,
Yang Y,
Zhou AF,
Chen R,
Yang L,
Scorpio DG,
McDermott AB ,
Shapiro L,
Carragher B,
Potter CS,
Mascola JR,
Kwong PD
(2018) Nat. Med. , 24 , 857 - 867
,
Kong R,
Cheng C,
Chuang GY,
Liu K ,
Louder MK ,
O'Dell S,
Rawi R,
Sastry M,
Shen CH,
Zhang B,
Zhou T,
Asokan M ,
Bailer RT,
Chambers M,
Chen X,
Choi CW,
Dandey VP,
Doria-Rose NA,
Druz A,
Eng ET ,
Farney SK,
Foulds KE,
Geng H,
Georgiev IS,
Gorman J ,
Hill KR,
Jafari AJ,
Kwon YD,
Lai YT ,
Lemmin T ,
McKee K,
Ohr TY,
Ou L,
Peng D,
Rowshan AP,
Sheng Z ,
Todd JP,
Tsybovsky Y,
Viox EG,
Wang Y,
Wei H,
Yang Y,
Zhou AF,
Chen R,
Yang L,
Scorpio DG,
McDermott AB ,
Shapiro L,
Carragher B,
Potter CS,
Mascola JR,
Kwong PD
(2018) Nat. Med. , 24 , 857 - 867