Structure of TRF1core in complex with telomeric nucleosome
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8ox1
Q-score: 0.579
Hu H, van Roon AM, Ghanim GE, Ahsan B, Oluwole AO, Peak-Chew SY, Robinson CV, Nguyen THD
Sci Adv (2023) 9 pp. eadi4148-eadi4148 [ DOI: doi:10.1126/sciadv.adi4148 Pubmed: 37624885 ]
- Telomeric repeat-binding factor 1 (50 kDa, Protein from Homo sapiens)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Trf1core in complex with telomeric nucleosome (Complex)
- Histone h2b type 1-c/e/f/g/i (14 kDa, Protein from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Human trf1core complex (Complex from Homo sapiens)
- Water (18 Da, Ligand)
- Human telomeric nucleosome (Complex from Homo sapiens)
- Telomeric dna g strand (46 kDa, DNA from Homo sapiens)
- Histone h2a type 1-c (14 kDa, Protein from Homo sapiens)
- Telomeric repeat-binding factor 1 (50 kDa, Protein from Homo sapiens)
- Telomeric dna c strand (43 kDa, DNA from Homo sapiens)
Structure of TRF1core in complex with telomeric nucleosome (4:1 complex)
Hu H, van Roon AM, Ghanim GE, Ahsan B, Oluwole AO, Peak-Chew SY, Robinson CV, Nguyen THD
Sci Adv (2023) 9 pp. eadi4148-eadi4148 [ DOI: doi:10.1126/sciadv.adi4148 Pubmed: 37624885 ]
- Human trf1core complex (Complex from Homo sapiens)
- Trf1core in complex with telomeric nucleosome (Complex)
- Human histone h3 (Protein from Homo sapiens)
- Human histone h2a (Protein from Homo sapiens)
- Telomeric dna g strand (DNA from Homo sapiens)
- Human histone h2b (Protein from Homo sapiens)
- Human histone h4 (Protein from Homo sapiens)
- Human trf1 protein (Protein from Homo sapiens)
- Human telomeric nucleosome (Complex from Homo sapiens)
- Telomeric dna c strand (DNA from Homo sapiens)
Structure of TDP-43 amyloid filaments from type A FTLD-TDP (individual 2)
Arseni D, Chen R, Murzin AG, Peak-Chew SY, Garringer HJ, Newell KL, Kametani F, Robinson AC, Vidal R, Ghetti B, Hasegawa M, Ryskeldi-Falcon B
Nature (2023) [ Pubmed: 37532939 DOI: 10.1038/s41586-023-06405-w ]
Image sets:
Structure of TDP-43 amyloid filaments from type A FTLD-TDP (individual 3)
Arseni D, Chen R, Murzin AG, Peak-Chew SY, Garringer HJ, Newell KL, Kametani F, Robinson AC, Vidal R, Ghetti B, Hasegawa M, Ryskeldi-Falcon B
Nature (2023) [ Pubmed: 37532939 DOI: 10.1038/s41586-023-06405-w ]
Image sets:
Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 1)
Arseni D, Chen R, Murzin AG, Peak-Chew SY, Garringer HJ, Newell KL, Kametani F, Robinson AC, Vidal R, Ghetti B, Hasegawa M, Ryskeldi-Falcon B
Nature (2023) 620 pp. 898-903 [ Pubmed: 37532939 DOI: doi:10.1038/s41586-023-06405-w ]
Structure of TDP-43 amyloid filaments from type A FTLD-TDP (individual 2, variant 2)
Arseni D, Chen R, Murzin AG, Peak-Chew SY, Garringer HJ, Newell KL, Kametani F, Robinson AC, Vidal R, Ghetti B, Hasegawa M, Ryskeldi-Falcon B
Nature (2023) 620 pp. 898-903 [ Pubmed: 37532939 DOI: doi:10.1038/s41586-023-06405-w ]
Structure of TDP-43 amyloid filaments from type A FTLD-TDP (individual 3, variant 1)
Arseni D, Chen R, Murzin AG, Peak-Chew SY, Garringer HJ, Newell KL, Kametani F, Robinson AC, Vidal R, Ghetti B, Hasegawa M, Ryskeldi-Falcon B
Nature (2023) 620 pp. 898-903 [ Pubmed: 37532939 DOI: doi:10.1038/s41586-023-06405-w ]
Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 1)
Resolution: 2.39 Å
EM Method: Helical reconstruction
Fitted PDBs: 8cg3
Q-score: 0.698
Arseni D, Chen R, Murzin AG, Peak-Chew SY, Garringer HJ, Newell KL, Kametani F, Robinson AC, Vidal R, Ghetti B, Hasegawa M, Ryskeldi-Falcon B
Nature (2023) 620 pp. 898-903 [ Pubmed: 37532939 DOI: doi:10.1038/s41586-023-06405-w ]
Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 2)
Resolution: 2.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 8cgg
Q-score: 0.67
Arseni D, Chen R, Murzin AG, Peak-Chew SY, Garringer HJ, Newell KL, Kametani F, Robinson AC, Vidal R, Ghetti B, Hasegawa M, Ryskeldi-Falcon B
Nature (2023) 620 pp. 898-903 [ Pubmed: 37532939 DOI: doi:10.1038/s41586-023-06405-w ]
Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 3)
Resolution: 2.68 Å
EM Method: Helical reconstruction
Fitted PDBs: 8cgh
Q-score: 0.668
Arseni D, Chen R, Murzin AG, Peak-Chew SY, Garringer HJ, Newell KL, Kametani F, Robinson AC, Vidal R, Ghetti B, Hasegawa M, Ryskeldi-Falcon B
Nature (2023) 620 pp. 898-903 [ Pubmed: 37532939 DOI: doi:10.1038/s41586-023-06405-w ]