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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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initial_angle_assignment_type:"MAXIMUM LIKELIHOOD" AND author_name:"Wang P" AND author_name:"Fu W" AND author_name:"Hao X" AND xref_links:"cpx" AND author_name:"An R"

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EMD-34044

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SARS-CoV-2 BA.2.75 S Trimer in complex with ACE2(state2)

Release date: Oct. 19, 2022
Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 7yr3
Q-score: 0.314

Cao Y, Song W, Wang L, Liu P, Yue C, Jian F, Yu Y, Yisimayi A, Wang P, Wang Y, Zhu Q, Deng J, Fu W, Yu L, Zhang N, Wang J, Xiao T, An R, Wang J, Liu L, Yang S, Niu X, Gu Q, Shao F, Hao X, Meng B, Gupta RK, Jin R, Wang Y, Xie XS, Wang X

Cell Host Microbe (2022) 30 pp. 1527- [ Pubmed: 36270286 DOI: doi:10.1016/j.chom.2022.09.018 ]

Sample:

2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Ba.2.75 spike trimer (Complex from Homo sapiens)
Chloride ion (35 Da, Ligand)
Water (18 Da, Ligand)
Ace2 (Complex)
Ba.2.75 spike trimer in complex with ace2 (state2) (Complex from Severe acute respiratory syndrome coronavirus 2)
Zinc ion (65 Da, Ligand)
Angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)

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