Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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primary_citation_author:"Chen J" AND author_orcid:"0000-0003-0884-231x"

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EMD-29736

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Cryo-EM structure of the TUG891 bound GPR120-Giq complex

Release date: March 8, 2023
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8g59
Q-score: 0.548

Mao C, Xiao P, Tao XN, Qin J, He QT, Zhang C, Guo SC, Du YQ, Chen LN, Shen DD, Yang ZS, Zhang HQ, Huang SM, He YH, Cheng J, Zhong YN, Shang P, Chen J, Zhang DL, Wang QL, Liu MX, Li GY, Guo Y, Xu HE, Wang C, Zhang C, Feng S, Yu X, Zhang Y, Sun JP

Science (2023) 380 pp. eadd6220-eadd6220 [ DOI: doi:10.1126/science.add6220 Pubmed: 36862765 ]

Sample:

Free fatty acid receptor 4 (40 kDa, Protein from Homo sapiens)
Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
Guanine nucleotide-binding protein g(q) subunit alpha (40 kDa, Protein from Homo sapiens)
Cryo-em structure of the tug891 bound gpr120-giq complex (Complex from Homo sapiens)
Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
Scfv16 (30 kDa, Protein from Homo sapiens)
3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid (364 Da, Ligand)

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