Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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author:"Ben LH" AND citation_journal_name:"SCI TRANSL MED"

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EMD-28523

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Structure of interleukin receptor common gamma chain (IL2Rgamma) in complex with two antibodies

Release date: Jan. 25, 2023
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8epa
Q-score: 0.433

Le Floc'h A, Nagashima K, Birchard D, Scott G, Ben LH, Ajithdoss D, Gayvert K, Romero Hernandez A, Herbin O, Tay A, Farrales P, Korgaonkar CK, Pan H, Shah S, Kamat V, Chatterjee I, Popke J, Oyejide A, Lim WK, Kim JH, Huang T, Franklin M, Olson W, Norton T, Perlee L, Yancopoulos GD, Murphy AJ, Sleeman MA, Orengo JM

Sci Transl Med (2023) 15 pp. eabo0205-eabo0205 [ DOI: doi:10.1126/scitranslmed.abo0205 Pubmed: 36630481 ]

Sample:

Regn7257 fab heavy chain (23 kDa, Protein from Mus musculus)
Cytokine receptor common subunit gamma (31 kDa, Protein from Homo sapiens)
Regn9432 fab heavy chain (23 kDa, Protein from Mus musculus)
Complex of il2rgamma extracellular domain with fab fragments of antibodies regn7257 and regn9432 (Complex from Mus musculus)
Regn7257 fab light chain (23 kDa, Protein from Mus musculus)
Regn9432 fab light chain (23 kDa, Protein from Mus musculus)

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