The cryo-EM structure of human sphingomyelin synthase-related protein in complex with ceramide
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 8ijq
Q-score: 0.461
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 8ijr
Q-score: 0.485
Hu K, Zhang Q, Chen Y, Yang J, Xia Y, Rao B, Li S, Shen Y, Cao M, Lu H, Qin A, Jiang XC, Yao D, Zhao J, Zhou L, Cao Y
Nat Struct Mol Biol (2024) 31 pp. 884-895 [ DOI: doi:10.1038/s41594-024-01237-2 Pubmed: 38388831 ]
- Sphingomyelin synthase-related protein 1 (48 kDa, Protein from Homo sapiens)
- (2s)-1-(hexadecanoyloxy)-3-hydroxypropan-2-yl (11z)-octadec-11-enoate (594 Da, Ligand)
- The cryo-em structure of human sphingomyelin synthase-related protein in complex with diacylglycerol/phosphoethanolamine (Complex from Homo sapiens)
- Phosphoric acid mono-(2-amino-ethyl) ester (141 Da, Ligand)
Resolution: 3.74 Å
EM Method: Single-particle
Fitted PDBs: 8w9w
Q-score: 0.377
Hu K, Zhang Q, Chen Y, Yang J, Xia Y, Rao B, Li S, Shen Y, Cao M, Lu H, Qin A, Jiang XC, Yao D, Zhao J, Zhou L, Cao Y
Nat Struct Mol Biol (2024) 31 pp. 884-895 [ DOI: doi:10.1038/s41594-024-01237-2 Pubmed: 38388831 ]
- ~{n}-[(~{z},2~{s},3~{r})-1,3-bis(oxidanyl)heptadec-4-en-2-yl]dodecanamide (467 Da, Ligand)
- Sphingomyelin synthase-related protein 1 (31 kDa, Protein from Homo sapiens)
- Phosphoric acid mono-(2-amino-ethyl) ester (141 Da, Ligand)
- The cryo-em structure of human sphingomyelin synthase-related protein in complex with ceramide/phosphoethanolamine (Complex from Homo sapiens)
The cryo-EM structure of human ERAD retro-translocation complex
Resolution: 3.61 Å
EM Method: Single-particle
Fitted PDBs: 7y53
Q-score: 0.366
Rao B, Wang Q, Yao D, Xia Y, Li W, Xie Y, Li S, Cao M, Shen Y, Qin A, Zhao J, Cao Y
Sci Adv (2023) 9 pp. eadi5656-eadi5656 [ Pubmed: 37831771 DOI: doi:10.1126/sciadv.adi5656 ]
- The cryo-em structure of human erad retro-translocation complex (650 kDa, Complex from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Transitional endoplasmic reticulum atpase (87 kDa, Protein from Homo sapiens)
- Derlin-1 (26 kDa, Protein from Homo sapiens)
The cryo-EM structure of human ERAD retro-translocation complex
Resolution: 4.51 Å
EM Method: Single-particle
Fitted PDBs: 7y59
Q-score: 0.22
Rao B, Wang Q, Yao D, Xia Y, Li W, Xie Y, Li S, Cao M, Shen Y, Qin A, Zhao J, Cao Y
Sci Adv (2023) 9 pp. eadi5656-eadi5656 [ Pubmed: 37831771 DOI: doi:10.1126/sciadv.adi5656 ]
- The cryo-em structure of human erad retro-translocation complex (650 kDa, Complex from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Transitional endoplasmic reticulum atpase (87 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Derlin-1 (30 kDa, Protein from Homo sapiens)