cryo-EM structure of human RNA polymerase III in elongating state
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7d58
Q-score: 0.014
Wang Q, Li S, Wan F, Xu Y, Wu Z, Cao M, Lan P, Lei M, Wu J
Nat Struct Mol Biol (2021) 28 pp. 220-227 [ Pubmed: 33558766 DOI: doi:10.1038/s41594-021-00557-x ]
- Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Non-template dna (12 kDa, DNA from Homo sapiens)
- Human pol3 ec (Complex from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
- Template dna (12 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
- Rna (6 kDa, RNA from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc4 (44 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Iron/sulfur cluster (351 Da, Ligand)
- Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)
cryo-EM structure of human RNA polymerase III in apo state
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7d59
Q-score: 0.391
Wang Q, Li S, Wan F, Xu Y, Wu Z, Cao M, Lan P, Lei M, Wu J
Nat Struct Mol Biol (2021) 28 pp. 220-227 [ DOI: doi:10.1038/s41594-021-00557-x Pubmed: 33558766 ]
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)
- Rna pol3 apo (Complex from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc4 (44 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Iron/sulfur cluster (351 Da, Ligand)
- Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)
Cryo-EM structure of yeast Ribonuclease MRP
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7c79
Q-score: 0.402
Lan P, Zhou B, Tan M, Li S, Cao M, Wu J, Lei M
Science (2020) 369 pp. 656-663 [ Pubmed: 32586950 DOI: doi:10.1126/science.abc0149 ]
- Ribonuclease mrp protein subunit rmp1 (23 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop3 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonuclease mrp rna subunit nme1 (108 kDa, RNA from Saccharomyces cerevisiae S288C)
- Magnesium ion (24 Da, Ligand)
- Ribonucleases p/mrp protein subunit pop1 (100 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop6 (18 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop7 (15 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonuclease mrp (Complex from Saccharomyces cerevisiae)
- Ribonuclease p/mrp protein subunit rpp1 (32 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop8 (15 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonuclease mrp protein subunit snm1 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Zinc ion (65 Da, Ligand)
- Rnases mrp/p 32.9 kda subunit (32 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonuclease p/mrp protein subunit pop5 (19 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
Cryo-EM structure of yeast Ribonuclease MRP with substrate ITS1
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7c7a
Q-score: 0.404
Lan P, Zhou B, Tan M, Li S, Cao M, Wu J, Lei M
Science (2020) 369 pp. 656-663 [ Pubmed: 32586950 DOI: doi:10.1126/science.abc0149 ]
- Internal transcribed spacer 1 (6 kDa, RNA from Saccharomyces cerevisiae)
- Ribonucleases p/mrp protein subunit pop3 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonuclease mrp rna subunit nme1 (108 kDa, RNA from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Zinc ion (65 Da, Ligand)
- Ribonuclease mrp protein subunit snm1 (22 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonuclease p/mrp protein subunit pop5 (19 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop8 (15 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- Rnases mrp/p 32.9 kda subunit (32 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop1 (100 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonuclease mrp with substrate its1 (Complex from Saccharomyces cerevisiae)
- Ribonucleases p/mrp protein subunit pop7 (15 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonucleases p/mrp protein subunit pop6 (18 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonuclease mrp protein subunit rmp1 (23 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ribonuclease p/mrp protein subunit rpp1 (32 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))