Electron Microscopy Data Bank

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cryo-EM structure of human RNA polymerase III in elongating state

Release date: Feb. 17, 2021
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7d58
Q-score: 0.014

Wang Q, Li S, Wan F, Xu Y, Wu Z, Cao M, Lan P, Lei M, Wu J

Nat Struct Mol Biol (2021) 28 pp. 220-227 [ Pubmed: 33558766 DOI: doi:10.1038/s41594-021-00557-x ]

Sample:

Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
Non-template dna (12 kDa, DNA from Homo sapiens)
Human pol3 ec (Complex from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
Template dna (12 kDa, DNA from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
Rna (6 kDa, RNA from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc4 (44 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
Iron/sulfur cluster (351 Da, Ligand)
Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)

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