Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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author:"Crispin M" AND author_name:"De Taeye Sw" AND author_orcid:"0000-0003-1548-790x" AND author_name:"Van Den Kerkhof Tl"

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EMD-8299

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AMC011 HIV-1 Env SOSIP trimer in complex with autologous anti-HIV antibody ACS202

Release date: Sept. 21, 2016
Resolution: 21.0 Å
EM Method: Single-particle

van Gils MJ, van den Kerkhof TL, Ozorowski G, Cottrell CA, Sok D, Pauthner M, Pallesen J, de Val N, Yasmeen A, de Taeye SW, Schorcht A, Gumbs S, Johanna I, Saye-Francisco K, Liang CH, Landais E, Nie X, Pritchard LK, Crispin M, Kelsoe G, Wilson IA, Schuitemaker H, Klasse PJ, Moore JP, Burton DR, Ward AB, Sanders RW

Nat Microbiol (2016) 2 pp. 16199-16199 [ Pubmed: 27841852 DOI: doi:10.1038/nmicrobiol.2016.199 ]

Sample:

Amc011 hiv-1 env trimer in complex with three copies of anti-hiv antibody acs202 fragment antigen binding (570 kDa, Complex from Human immunodeficiency virus 1)

EMD-8302

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HIV Clade B Env SOSIP ectodomain trimer from the Amsterdam Cohort Study patient AMC011 in complex with Fab from IgG PGV04

Release date: Sept. 21, 2016
Resolution: 6.2 Å
EM Method: Single-particle

van Gils MJ, van den Kerkhof TL, Ozorowski G, Cottrell CA, Sok D, Pauthner M, Pallesen J, de Val N, Yasmeen A, de Taeye SW, Schorcht A, Gumbs S, Johanna I, Saye-Francisco K, Liang CH, Landais E, Nie X, Pritchard LK, Crispin M, Kelsoe G, Wilson IA, Schuitemaker H, Klasse PJ, Moore JP, Burton DR, Ward AB, Sanders RW

Nat Microbiol (2016) 2 pp. 16199-16199 [ DOI: doi:10.1038/nmicrobiol.2016.199 Pubmed: 27841852 ]

Sample:

Amc011v.4.2_sosip (Protein from Human immunodeficiency virus 1)
Pgv04 fab hc (Protein from Homo sapiens)
Hiv clade b env sosip ectodomain trimer from the amsterdam cohort study patient amc011 in complex with fab from igg pgv04 (600 kDa, Complex)
Pgv04 fab lc (Protein from Homo sapiens)

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