Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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author:"Cupo A" AND author_name:"Julien JP" AND microscope_name:"FEI TECNAI SPIRIT" AND electron_source:"TUNGSTEN HAIRPIN"

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EMD-5983

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Structure of 2G12 (Fab)2 in Complex with Soluble and Fully Glycosylated HIV-1 Env by Negative-Stain Single Particle Electron Microscopy

Release date: Aug. 6, 2014
Resolution: 26.0 Å
EM Method: Single-particle

Murin CD, Julien JP, Sok D, Stanfield RL, Khayat R, Cupo A, Moore JP, Burton DR, Wilson IA, Ward AB

J Virol (2014) 88 pp. 10177-10188 [ Pubmed: 24965454 DOI: doi:10.1128/JVI.01229-14 ]

Sample:

Human monoclonal antibody 2g12 igg1 fab fragment (100 kDa, Protein from Homo sapiens)
Fab fragment of 2g12 monoclonal antibody and soluble, two-domain cd4 (domains 1 and 2, scd4) bound to hiv-1 env bg505.664 (730 kDa, Sample)
Hiv-1 env (360 kDa, Protein from Human immunodeficiency virus 1)
Soluble cd4 (23 kDa, Protein from Homo sapiens)

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