Taf15 amyloid filaments - Individual 1, motor cortex
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2023) 625 pp. 345-351 [ DOI: 10.1038/s41586-023-06801-2 Pubmed: 38057661 ]
Image sets:
Taf15 amyloid filaments - Individual 2
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2023) 625 pp. 345-351 [ DOI: 10.1038/s41586-023-06801-2 Pubmed: 38057661 ]
Image sets:
Taf15, TMEM106B and Aß42 amyloid filaments - Individual 4, frontal cortex
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2023) 625 pp. 345-351 [ DOI: 10.1038/s41586-023-06801-2 Pubmed: 38057661 ]
Image sets:
Taf15, TMEM106B and Aß42 amyloid filaments - Individual 4, brainstem
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2023) 625 pp. 345-351 [ DOI: 10.1038/s41586-023-06801-2 Pubmed: 38057661 ]
Image sets:
Resolution: 2.9 Å
EM Method: Helical reconstruction
Fitted PDBs: 8seh
Q-score: 0.553
Fernandez A, Hoq MR, Hallinan GI, Li D, Bharath SR, Vago FS, Zhang X, Ozcan KA, Newell KL, Garringer HJ, Jiang W, Ghetti B, Vidal R
Nat Struct Mol Biol (2024) 31 pp. 903-909 [ DOI: doi:10.1038/s41594-024-01252-3 Pubmed: 38553642 ]
- Microtubule-associated protein tau (7 kDa, Protein from Homo sapiens)
- Helical filaments (Tissue from Homo sapiens)
Resolution: 2.9 Å
EM Method: Helical reconstruction
Fitted PDBs: 8sei
Q-score: 0.556
Fernandez A, Hoq MR, Hallinan GI, Li D, Bharath SR, Vago FS, Zhang X, Ozcan KA, Newell KL, Garringer HJ, Jiang W, Ghetti B, Vidal R
Nat Struct Mol Biol (2024) 31 pp. 903-909 [ DOI: doi:10.1038/s41594-024-01252-3 Pubmed: 38553642 ]
- Microtubule-associated protein tau (7 kDa, Protein from Homo)
- Sf tau (Tissue from Homo sapiens)
Type I beta-amyloid 42 Filaments from Down syndrome
Resolution: 3.17 Å
EM Method: Helical reconstruction
Fitted PDBs: 8sej
Q-score: 0.472
Fernandez A, Hoq MR, Hallinan GI, Li D, Bharath SR, Vago FS, Zhang X, Ozcan KA, Newell KL, Garringer HJ, Jiang W, Ghetti B, Vidal R
Nat Struct Mol Biol (2024) 31 pp. 903-909 [ DOI: doi:10.1038/s41594-024-01252-3 Pubmed: 38553642 ]
- Amyloid-beta protein 42 (3 kDa, Protein from Homo sapiens)
- Type i beta amyloid 42 (Tissue from Homo sapiens)
Type IIIa beta-amyloid 40 Filaments from Down syndrome
Resolution: 3.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 8sek
Q-score: 0.481
Fernandez A, Hoq MR, Hallinan GI, Li D, Bharath SR, Vago FS, Zhang X, Ozcan KA, Newell KL, Garringer HJ, Jiang W, Ghetti B, Vidal R
Nat Struct Mol Biol (2024) 31 pp. 903-909 [ DOI: doi:10.1038/s41594-024-01252-3 Pubmed: 38553642 ]
- Type iiib beta-amyloid 40 filament (4 kDa, Protein from Homo sapiens)
- Type iiia beta amyloid 40 (Tissue from Homo sapiens)
Type IIIb beta-amyloid 40 Filaments from Down Syndrome
Resolution: 3.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 8sel
Q-score: 0.405
Fernandez A, Hoq MR, Hallinan GI, Li D, Bharath SR, Vago FS, Zhang X, Ozcan KA, Newell KL, Garringer HJ, Jiang W, Ghetti B, Vidal R
Nat Struct Mol Biol (2024) 31 pp. 903-909 [ DOI: doi:10.1038/s41594-024-01252-3 Pubmed: 38553642 ]
Taf15 amyloid filaments - Individual 3
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2023) 625 pp. 345-351 [ DOI: 10.1038/s41586-023-06801-2 Pubmed: 38057661 ]
Image sets: