Resolution: 2.77 Å
EM Method: Single-particle
Fitted PDBs: 8j6m
Q-score: 0.587
Zhang J, Zhan C, Fan J, Wu D, Zhang R, Wu D, Chen X, Lu Y, Li M, Lin M, Gong J, Jiang D
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01276-9 Pubmed: 38664565 ]
- Sodium ion (22 Da, Ligand)
- Green fluorescent protein,sid1 transmembrane family member 1 (124 kDa, Protein from Homo sapiens)
- Oleic acid (282 Da, Ligand)
- T1 (Complex from Homo sapiens)
- Water (18 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Zinc ion (65 Da, Ligand)
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8j6o
Q-score: 0.403
Zhang J, Zhan C, Fan J, Wu D, Zhang R, Wu D, Chen X, Lu Y, Li M, Lin M, Gong J, Jiang D
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01276-9 Pubmed: 38664565 ]
- Green fluorescent protein (fragment),sid1 transmembrane family member 2 (124 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- T2 (Complex from Homo sapiens)
Cardiac sodium channel in complex with LqhIII
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7xsu
Q-score: 0.433
To Be Published
- Sodium channel protein type 5 subunit alpha,g protein/gfp fusion protein (209 kDa, Protein from Recombinant vesicular stomatitis Indiana virus rVSV-G/GFP)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Lqhiii (Complex)
- Alpha-like toxin lqh3 (7 kDa, Protein from Leiurus quinquestriatus hebraeus)
- Beta-d-mannopyranose (180 Da, Ligand)
- Cardiac sodium channel with a gfp-flag tag fused at the c-terminus (Complex from Rattus norvegicus)
- (3beta,14beta,17beta,25r)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en (544 Da, Ligand)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
- Cardiac sodium channel complexed with toxin lqhiii (300 kDa, Complex)
Resolution: 2.77 Å
EM Method: Single-particle
Fitted PDBs: 8hip
Q-score: 0.596
Zhang J, Zhan C, Fan J, Wu D, Zhang R, Wu D, Chen X, Lu Y, Li M, Lin M, Gong J, Jiang D
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01276-9 Pubmed: 38664565 ]
- Dsrna transporter complex (Complex from Homo sapiens)
- Systemic rna interference defective protein 1 (88 kDa, Protein from Homo sapiens)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
- Zinc ion (65 Da, Ligand)
Resolution: 3.71 Å
EM Method: Single-particle
Fitted PDBs: 8hke
Q-score: 0.431
Zhang J, Zhan C, Fan J, Wu D, Zhang R, Wu D, Chen X, Lu Y, Li M, Lin M, Gong J, Jiang D
Nat Struct Mol Biol (2024) [ DOI: doi:10.1038/s41594-024-01276-9 Pubmed: 38664565 ]
- Dsrna transporter (Complex from Homo sapiens)
- Rna (37-mer) (11 kDa, RNA from Homo sapiens)
- Systemic rna interference defective protein 1 (88 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Rna (37-mer) (11 kDa, RNA from Homo sapiens)
Human VMAT2 complex with serotonin
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8jsw
Q-score: 0.578
Wu D, Chen Q, Yu Z, Huang B, Zhao J, Wang Y, Su J, Zhou F, Yan R, Li N, Zhao Y, Jiang D
Nature (2024) 626 pp. 427-434 [ Pubmed: 38081299 DOI: doi:10.1038/s41586-023-06926-4 ]
- Transportera (Complex from Homo sapiens)
- Synaptic vesicular amine transporter (49 kDa, Protein from Homo sapiens)
- Serotonin (176 Da, Ligand)
Human VMAT2 complex with tetrabenazine
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 8jta
Q-score: 0.506
Wu D, Chen Q, Yu Z, Huang B, Zhao J, Wang Y, Su J, Zhou F, Yan R, Li N, Zhao Y, Jiang D
Nature (2024) 626 pp. 427-434 [ Pubmed: 38081299 DOI: doi:10.1038/s41586-023-06926-4 ]
- Transporter2 (Complex from Homo sapiens)
- Synaptic vesicular amine transporter (49 kDa, Protein from Homo sapiens)
- Tetrabenazine (317 Da, Ligand)
Human VMAT2 complex with reserpine
Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 8jtc
Q-score: 0.481
Wu D, Chen Q, Yu Z, Huang B, Zhao J, Wang Y, Su J, Zhou F, Yan R, Li N, Zhao Y, Jiang D
Nature (2024) 626 pp. 427-434 [ Pubmed: 38081299 DOI: doi:10.1038/s41586-023-06926-4 ]
- Transportera (Complex from Homo sapiens)
- Synaptic vesicular amine transporter (49 kDa, Protein from Homo sapiens)
- Reserpine (608 Da, Ligand)
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8hir
Q-score: 0.518
Zhang J, Liu S, Fan J, Yan R, Huang B, Zhou F, Yuan T, Gong J, Huang Z, Jiang D
Cell Rep (2023) 42 pp. 112858-112858 [ Pubmed: 37494189 DOI: doi:10.1016/j.celrep.2023.112858 ]
- Potassium ion (39 Da, Ligand)
- Potassium channel subfamily t member 1 (139 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Potassium channel (Complex from Homo sapiens)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
- Sodium ion (22 Da, Ligand)