Prefusion RSV F Bound to Lonafarnib and D25 Fab
Yang Q, Xue B, Liu F, Lu Y, Tang J, Yan M, Wu Q, Chen R, Zhou A, Liu L, Liu J, Qu C, Wu Q, Fu M, Zhong J, Dong J, Chen S, Wang F, Zhou Y, Zheng J, Peng W, Shang J, Chen X
Signal Transduct Target Ther (2024) 9 pp. 144-144 [ DOI: doi:10.1038/s41392-024-01858-5 Pubmed: 38853183 ]
- 4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5h-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide (638 Da, Ligand)
- Fusion glycoprotein f0,fibritin (64 kDa, Protein from Enterobacteria phage T4)
- Prefusion rsv f bound to lonafarnib and d25 fab (Complex from Human respiratory syncytial virus A (strain A2))
- D25 heavy chain (24 kDa, Protein from Homo sapiens)
- D25 light chain (23 kDa, Protein from Homo sapiens)
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 8gk7
Q-score: 0.364
Wang H, Ishchenko A, Skudlarek J, Shen P, Dzhekieva L, Painter RE, Chen YT, Bukhtiyarova M, Leithead A, Tracy R, Babaoglu K, Bahnck-Teets C, Buevich A, Cabalu TD, Labroli M, Lange H, Lei Y, Li W, Liu J, Mann PA, Meng T, Mitchell HJ, Mulhearn J, Scapin G, Sha D, Shaw AW, Si Q, Tong L, Wu C, Wu Z, Xiao JC, Xu M, Zhang LK, McKenney D, Miller RR, Black TA, Cooke A, Balibar CJ, Klein DJ, Raheem I, Walker SS
Nat Microbiol (2024) 9 pp. 1244-1255 [ Pubmed: 38649414 DOI: doi:10.1038/s41564-024-01667-0 ]
- Msba complexed with cerastecin c (450 kDa, Complex from Acinetobacter baumannii)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- 2-[(4-butylbenzene-1-sulfonyl)amino]-5-[(3-{4-[(4-butylbenzene-1-sulfonyl)amino]-3-carboxyanilino}-3-oxopropyl)carbamoyl]benzoic acid (778 Da, Ligand)
- Lipid a export atp-binding/permease protein msba (66 kDa, Protein from Acinetobacter baumannii)
Tertiary structure of an individual particle of self-folding RNA polymer (particle #011)
Tertiary structure of an individual particle of self-folding RNA polymer (particle #012)
Tertiary structure of an individual particle of self-folding RNA polymer (particle #013)
Tertiary structure of an individual particle of self-folding RNA polymer (particle #014)
Tertiary structure of an individual particle of self-folding RNA polymer (particle #015)
Tertiary structure of an individual particle of self-folding RNA polymer (particle #016)
Tertiary structure of an individual particle of self-folding RNA polymer (particle #017)