Cytoplasmic ring of the human nuclear pore complex from isolated HeLa nuclear envelopes
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ Pubmed: 35679397 DOI: doi:10.1126/science.abm9506 ]
Structure of nuclear pore complex from HEK cells with GP210 knockout
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ Pubmed: 35679397 DOI: doi:10.1126/science.abm9506 ]
Nuclear pore complex from intact HeLa cells
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ Pubmed: 35679397 DOI: doi:10.1126/science.abm9506 ]
Inner/spoke ring of the human nuclear pore complex from isolated HeLa nuclear envelopes.
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ Pubmed: 35679397 DOI: doi:10.1126/science.abm9506 ]
Nuclear ring of the human nuclear pore complex from isolated HeLa nuclear envelopes
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ Pubmed: 35679397 DOI: doi:10.1126/science.abm9506 ]
Human nuclear pore complex (dilated)
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ Pubmed: 35679397 DOI: doi:10.1126/science.abm9506 ]
- Aladin (59 kDa, Protein from human)
- Nucleoporin p58/p45 (60 kDa, Protein from human)
- Nuclear pore complex protein nup133 (129 kDa, Protein from human)
- Nucleoporin nup188 homolog (196 kDa, Protein from human)
- Protein sec13 homolog (35 kDa, Protein from human)
- Nucleoporin nup43 (42 kDa, Protein from human)
- Nuclear pore complex protein nup160 (162 kDa, Protein from human)
- Human nuclear pore complex from hek cells (Cellular component from Homo sapiens)
- Nucleoporin nup37 (36 kDa, Protein from human)
- Nucleoporin nup35 (34 kDa, Protein from human)
- Nuclear pore complex protein nup205 (228 kDa, Protein from human)
- Nuclear pore complex protein nup98 (91 kDa, Protein from human)
- E3 sumo-protein ligase ranbp2 (358 kDa, Protein from human)
- Nuclear pore complex protein nup93 (93 kDa, Protein from human)
- Protein elys (252 kDa, Protein from human)
- Nuclear pore membrane glycoprotein 210 (205 kDa, Protein from human)
- Nucleoporin ndc1 (76 kDa, Protein from human)
- Nuclear pore complex protein nup155 (155 kDa, Protein from human)
- Nuclear pore complex protein nup214 (213 kDa, Protein from human)
- Nuclear pore complex protein nup96 (106 kDa, Protein from human)
- Nucleoporin seh1 (39 kDa, Protein from human)
- Nuclear pore complex protein nup107 (106 kDa, Protein from human)
- Nuclear pore complex protein nup88 (83 kDa, Protein from human)
- Nuclear pore complex protein nup85 (75 kDa, Protein from human)
- Nucleoporin p54 (55 kDa, Protein from human)
- Nuclear pore glycoprotein p62 (53 kDa, Protein from human)
Human nuclear pore complex (constricted)
Resolution: 12.0 Å
EM Method: Subtomogram averaging
Fitted PDBs: 7r5k
Q-score: 0.034
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ Pubmed: 35679397 DOI: doi:10.1126/science.abm9506 ]
- Aladin (59 kDa, Protein from human)
- Nuclear pore complex (120 MDa, Cellular component from Homo sapiens)
- Nucleoporin p58/p45 (60 kDa, Protein from human)
- Nuclear pore complex protein nup133 (129 kDa, Protein from human)
- Nucleoporin nup188 homolog (196 kDa, Protein from human)
- Protein sec13 homolog (35 kDa, Protein from human)
- Nucleoporin nup43 (42 kDa, Protein from human)
- Nuclear pore complex protein nup160 (162 kDa, Protein from human)
- Nucleoporin nup37 (36 kDa, Protein from human)
- Nucleoporin nup35 (34 kDa, Protein from human)
- Nuclear pore complex protein nup205 (228 kDa, Protein from human)
- Nuclear pore complex protein nup98 (91 kDa, Protein from human)
- E3 sumo-protein ligase ranbp2 (358 kDa, Protein from human)
- Nuclear pore complex protein nup93 (93 kDa, Protein from human)
- Protein elys (252 kDa, Protein from human)
- Nuclear pore membrane glycoprotein 210 (205 kDa, Protein from human)
- Nucleoporin ndc1 (76 kDa, Protein from human)
- Nuclear pore complex protein nup155 (155 kDa, Protein from human)
- Nuclear pore complex protein nup214 (213 kDa, Protein from human)
- Nuclear pore complex protein nup96 (106 kDa, Protein from human)
- Nucleoporin seh1 (39 kDa, Protein from human)
- Nuclear pore complex protein nup107 (106 kDa, Protein from human)
- Nuclear pore complex protein nup88 (83 kDa, Protein from human)
- Nuclear pore complex protein nup85 (75 kDa, Protein from human)
- Nucleoporin p54 (55 kDa, Protein from human)
- Nuclear pore glycoprotein p62 (53 kDa, Protein from human)
cryoEM structure of human Nup155 (residues 19-981)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7r1y
Q-score: 0.48
Mosalaganti S, Obarska-Kosinska A, Siggel M, Taniguchi R, Turonova B, Zimmerli CE, Buczak K, Schmidt FH, Margiotta E, Mackmull MT, Hagen WJH, Hummer G, Kosinski J, Beck M
Science (2022) 376 pp. eabm9506-eabm9506 [ Pubmed: 35679397 DOI: doi:10.1126/science.abm9506 ]
- Nup155 from homo sapiens (Cellular component from Homo sapiens)
- Nuclear pore complex protein nup155 (154 kDa, Protein from Homo sapiens)
CryoEM structure of C. thermophilum fatty acid synthase from native cell extract
Kastritis PL, O'Reilly FJ, Bock T, Li Y, Rogon MZ, Buczak K, Romanov N, Betts MJ, Bui KH, Hagen WJ, Hennrich ML, Mackmull MT, Rappsilber J, Russell RB, Bork P, Beck M, Gavin AC
Mol Syst Biol (2017) 13 pp. 936-936 [ DOI: doi:10.15252/msb.20167412 Pubmed: 28743795 ]
- Fatty acid synthase beta subunit (Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Fatty acid synthase alpha subunit (Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- The fatty acid synthase complex (fas1+fas2, a6b6) (2 MDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
Electron microscopy of the human Nup107 subcomplex
Bui KH, von Appen A, DiGuilio AL, Ori A, Sparks L, Mackmull MT, Bock T, Hagen W, Andres-Pons A, Glavy JS, Beck M
Cell (2013) 155 pp. 1233-1243 [ Pubmed: 24315095 DOI: doi:10.1016/j.cell.2013.10.055 ]