Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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author:"Maslen S" AND software_ft:"CTFFIND" AND microscope_name:"FEI TITAN KRIOS"

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EMD-13097

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human DEPTOR in a complex with mutant human mTORC1 A1459P

Release date: Sept. 8, 2021
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 7owg
Q-score: 0.293

Heimhalt M, Berndt A, Wagstaff J, Anandapadamanaban M, Perisic O, Maslen S, McLaughlin S, Yu CW, Masson GR, Boland A, Ni X, Yamashita K, Murshudov GN, Skehel M, Freund SM, Williams RL

eLife (2021) 10 [ DOI: doi:10.7554/eLife.68799 Pubmed: 34519269 ]

Sample:

Regulatory-associated protein of mtor (149 kDa, Protein from Homo sapiens)
Mtorc1 with mutant a1459p mtor (Complex from Homo sapiens)
Complex of human mutant mtorc1 a1459p with the inhibitory protein deptor (46 MDa, Complex)
Dep domain-containing mtor-interacting protein (46 kDa, Protein from Homo sapiens)
Target of rapamycin complex subunit lst8 (35 kDa, Protein from Homo sapiens)
Serine/threonine-protein kinase mtor (287 kDa, Protein from Homo sapiens)
Deptor (Complex from Homo sapiens)

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