Cryo-EM structure of CCHFV envelope protein Gc trimer in complex with Gc13 Fab
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8jkd
Q-score: 0.612
CCHFV envelope protein Gc in complex with Gc8
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8jlw
Q-score: 0.513
Li L, Chong T, Peng L, Liu Y, Rao G, Fu Y, Shu Y, Shen J, Xiao Q, Liu J, Li J, Deng F, Yan B, Hu Z, Cao S, Wang M
PLoS Pathog (2024) 20 pp. e1011948-e1011948 [ DOI: doi:10.1371/journal.ppat.1011948 Pubmed: 38300972 ]
- Glycoprotein c,cchfv envelope protein gc fusion loops (65 kDa, Protein from Crimean-Congo hemorrhagic fever orthonairovirus)
- Mouse antibody gc8 light chain (11 kDa, Protein from Mus musculus)
- Mouse antibody gc8 heavy chain (12 kDa, Protein from Mus musculus)
- Cchfv envelope protein gc-gc8 complex (Complex from Crimean-Congo hemorrhagic fever virus strain IbAr10200)
CCHFV envelope protein Gc in complex with Gc13
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8jlx
Q-score: 0.51
Li L, Chong T, Peng L, Liu Y, Rao G, Fu Y, Shu Y, Shen J, Xiao Q, Liu J, Li J, Deng F, Yan B, Hu Z, Cao S, Wang M
PLoS Pathog (2024) 20 pp. e1011948-e1011948 [ DOI: doi:10.1371/journal.ppat.1011948 Pubmed: 38300972 ]
- Mouse antibody gc13 heavy chain (12 kDa, Protein from Mus musculus)
- Mouse antibody gc13 light chain (11 kDa, Protein from Mus musculus)
- Cchfv envelope protein gc-gc13 complex (Complex from Crimean-Congo hemorrhagic fever virus strain IbAr10200)
- Glycoprotein c,cchfv gc fusion loops (65 kDa, Protein from Crimean-Congo hemorrhagic fever orthonairovirus)
human KCNQ2-CaM-Ebio1 complex in the presence of PIP2
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8ijk
Q-score: 0.383
Zhang S, Ma D, Wang K, Li Y, Yang Z, Li X, Li J, He J, Mei L, Ye Y, Chen Z, Shen J, Hou P, Guo J, Zhang Q, Yang H
Nat Chem Biol (2024) [ DOI: doi:10.1038/s41589-023-01515-y Pubmed: 38167918 ]
- Potassium voltage-gated channel subfamily kqt member 2 (73 kDa, Protein from Homo sapiens)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
- Human kcnq2-cam-ebio1 complex in the presence of pip2 (Complex from Homo sapiens)
- N-(1,2-dihydroacenaphthylen-5-yl)-4-fluoranyl-benzamide (291 Da, Ligand)
human KCNQ2-CaM-Ebio1-S1 complex in the presence of PIP2
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8x43
Q-score: 0.328
Zhang S, Ma D, Wang K, Li Y, Yang Z, Li X, Li J, He J, Mei L, Ye Y, Chen Z, Shen J, Hou P, Guo J, Zhang Q, Yang H
Nat Chem Biol (2024) [ DOI: doi:10.1038/s41589-023-01515-y Pubmed: 38167918 ]
- Potassium voltage-gated channel subfamily kqt member 2 (73 kDa, Protein from Homo sapiens)
- N-(4-azanyl-1,2-dihydroacenaphthylen-5-yl)-4-fluoranyl-benzamide (306 Da, Ligand)
- Human kcnq2-cam-ebio1-s1 complex in the presence of pip2 (Cellular component from Homo sapiens)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
Cryo-EM structure of native RC-LH complex from Roseiflexus castenholzii at 10,000 lux
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8hju
Q-score: 0.603
Xin J, Shi Y, Zhang X, Yuan X, Xin Y, He H, Shen J, Blankenship RE, Xu X
eLife (2023) 12 [ DOI: doi:10.7554/eLife.88951 Pubmed: 37737710 ]
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Beta,psi-caroten-4-one (550 Da, Ligand)
- Multiheme_cytc domain-containing protein (34 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Alpha subunit of light-harvesting 1 (4 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Subunit y (4 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- 2-methyl-3-[(2e,6e,10e,14e,18e,22e,26e,30e,34e,38e)-3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,1 4,18,22,26,30,34,38,42-undecaen-1-yl]naphthalene-1,4-dione (921 Da, Ligand)
- Reaction center protein m chain (35 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Bacteriochlorophyll a (911 Da, Ligand)
- Subunit x (3 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- The native rc-lh complex (Complex from Roseiflexus castenholzii DSM 13941)
- Bacteriopheophytin a (889 Da, Ligand)
- Subunit z (6 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Diacyl glycerol (625 Da, Ligand)
- (1r)-2-{[{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11e)-octadec-11-enoate (749 Da, Ligand)
- Reaction center protein l chain (34 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Beta subunit of light-harvesting 1 (6 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Fe (iii) ion (55 Da, Ligand)
Cryo-EM structure of carotenoid-depleted RC-LH complex from Roseiflexus castenholzii at 10,000 lux
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8hjv
Q-score: 0.478
Xin J, Shi Y, Zhang X, Yuan X, Xin Y, He H, Shen J, Blankenship RE, Xu X
eLife (2023) 12 [ DOI: doi:10.7554/eLife.88951 Pubmed: 37737710 ]
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Beta,psi-caroten-4-one (550 Da, Ligand)
- Multiheme_cytc domain-containing protein (34 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Alpha subunit of light-harvesting 1 (4 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Subunit y (4 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- 2-methyl-3-[(2e,6e,10e,14e,18e,22e,26e,30e,34e,38e)-3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,1 4,18,22,26,30,34,38,42-undecaen-1-yl]naphthalene-1,4-dione (921 Da, Ligand)
- Reaction center protein m chain (35 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Bacteriochlorophyll a (911 Da, Ligand)
- Bacteriopheophytin a (889 Da, Ligand)
- Subunit z (6 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- (1r)-2-{[{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11e)-octadec-11-enoate (749 Da, Ligand)
- Reaction center protein l chain (34 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Beta subunit of light-harvesting 1 (6 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Fe (iii) ion (55 Da, Ligand)
- The carotenoid-depleted rc-lh complex (Complex from Roseiflexus castenholzii DSM 13941)
Cryo-EM structure of native RC-LH complex from Roseiflexus castenholzii at 100lux
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8j5o
Q-score: 0.606
Xin J, Shi Y, Zhang X, Yuan X, Xin Y, He H, Shen J, Blankenship RE, Xu X
eLife (2023) 12 [ DOI: doi:10.7554/eLife.88951 Pubmed: 37737710 ]
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Beta,psi-caroten-4-one (550 Da, Ligand)
- Subunit y (4 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Multiheme_cytc domain-containing protein (34 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Alpha subunit of light-harvesting 1 (4 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Subunit x (3 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Subunit z (6 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- 2-methyl-3-[(2e,6e,10e,14e,18e,22e,26e,30e,34e,38e)-3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,1 4,18,22,26,30,34,38,42-undecaen-1-yl]naphthalene-1,4-dione (921 Da, Ligand)
- Reaction center protein m chain (35 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Bacteriochlorophyll a (911 Da, Ligand)
- Bacteriopheophytin a (889 Da, Ligand)
- (1r)-2-{[{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11e)-octadec-11-enoate (749 Da, Ligand)
- Reaction center protein l chain (34 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Beta subunit of light-harvesting 1 (6 kDa, Protein from Roseiflexus castenholzii DSM 13941)
- Fe (iii) ion (55 Da, Ligand)
- The native rc-lh complex at 100lux (Complex from Roseiflexus castenholzii DSM 13941)