Cryo-EM structure of DiCas7-11 in complex with crRNA
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8wm4
Q-score: 0.435
Hong T, Luo Q, Ma H, Wang X, Li X, Shen C, Pang J, Wang Y, Chen Y, Zhang C, Su Z, Dong H, Tang X
Signal Transduct Target Ther (2024) 9 pp. 111-111 [ Pubmed: 38735995 DOI: doi:10.1038/s41392-024-01821-4 ]
- Binary complex of cas7-11 and crrna (Complex from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- Crispr-associated ramp family protein (183 kDa, Protein from Desulfonema ishimotonii)
- Crrna (38-mer) (12 kDa, RNA from Escherichia coli)
Cryo-EM structure of DiCas7-11-crRNA in complex with regulator
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8wmc
Q-score: 0.538
Hong T, Luo Q, Ma H, Wang X, Li X, Shen C, Pang J, Wang Y, Chen Y, Zhang C, Su Z, Dong H, Tang X
Signal Transduct Target Ther (2024) 9 pp. 111-111 [ Pubmed: 38735995 DOI: doi:10.1038/s41392-024-01821-4 ]
- Ternary complex of cas7-11_crrna_tpr-chat (Complex from Escherichia coli)
- Chat domain-containing protein (88 kDa, Protein from Desulfonema ishimotonii)
- Crispr-associated ramp family protein (183 kDa, Protein from Desulfonema ishimotonii)
- Zinc ion (65 Da, Ligand)
- Rna (38-mer) (12 kDa, RNA from Escherichia coli)
Cryo-EM structure of DiCas7-11 mutant in complex with crRNA
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8wmi
Q-score: 0.426
Hong T, Luo Q, Ma H, Wang X, Li X, Shen C, Pang J, Wang Y, Chen Y, Zhang C, Su Z, Dong H, Tang X
Signal Transduct Target Ther (2024) 9 pp. 111-111 [ Pubmed: 38735995 DOI: doi:10.1038/s41392-024-01821-4 ]
- Zinc ion (65 Da, Ligand)
- Crrna (39-mer) (12 kDa, RNA from Escherichia coli)
- Crispr-associated ramp family protein (183 kDa, Protein from Desulfonema ishimotonii)
- Binary complex of dicas7-11 mutant with crrna (Complex from Escherichia coli)
Cryo-EM structure of Cas7-11-crRNA bound to N-terminal of TPR-CHAT
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8wml
Q-score: 0.522
Hong T, Luo Q, Ma H, Wang X, Li X, Shen C, Pang J, Wang Y, Chen Y, Zhang C, Su Z, Dong H, Tang X
Signal Transduct Target Ther (2024) 9 pp. 111-111 [ Pubmed: 38735995 DOI: doi:10.1038/s41392-024-01821-4 ]
- Chat domain-containing protein (7 kDa, Protein from Desulfonema ishimotonii)
- Crispr-associated ramp family protein (183 kDa, Protein from Desulfonema ishimotonii)
- Ternary complex of cas7-11-crrna bound to n-terminal of tpr-chat (Complex from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- Crrna (38-mer) (12 kDa, RNA from Escherichia coli)
Structure of divisome complex FtsWIQLB
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8p1u
Q-score: 0.45
Yang L, Chen Y, Chang S, Shen C, Wang X, Zhang C, Zhang Z, Ding BS, Su Z, Dong H, Tang X
Cell Discov (2024) 10 pp. 2-2 [ Pubmed: 38172099 DOI: doi:10.1038/s41421-023-00629-w ]
- Probable peptidoglycan glycosyltransferase ftsw (43 kDa, Protein from Pseudomonas aeruginosa)
- Peptidoglycan d,d-transpeptidase ftsi (62 kDa, Protein from Pseudomonas aeruginosa)
- Cell division protein ftsq (32 kDa, Protein from Pseudomonas aeruginosa)
- Cell division protein ftsb (10 kDa, Protein from Pseudomonas aeruginosa)
- Cell division protein ftsl (11 kDa, Protein from Pseudomonas aeruginosa)
- Divisome complex ftswiqlb (Complex from Escherichia coli K-12)
Cryo-EM structure of the GPR34 receptor in complex with the antagonist YL-365
Resolution: 3.34 Å
EM Method: Single-particle
Fitted PDBs: 8iyx
Q-score: 0.448
Xia A, Yong X, Zhang C, Lin G, Jia G, Zhao C, Wang X, Hao Y, Wang Y, Zhou P, Yang X, Deng Y, Wu C, Chen Y, Zhu J, Tang X, Liu J, Zhang S, Zhang J, Xu Z, Hu Q, Zhao J, Yue Y, Yan W, Su Z, Wei Y, Zhou R, Dong H, Shao Z, Yang S
PNAS (2023) 120 pp. e2308435120-e2308435120 [ Pubmed: 37733739 DOI: doi:10.1073/pnas.2308435120 ]
- Probable g-protein coupled receptor 34,yl-365 (66 kDa, Protein from Homo sapiens)
- 1-[4-(3-chlorophenyl)phenyl]carbonyl-4-[2-(4-phenylmethoxyphenyl)ethanoylamino]piperidine-4-carboxylic acid (583 Da, Ligand)
- Cryo-em structure of the gpr34 receptor in complex with the antagonist yl-365 (Complex from Homo sapiens)
Complex Structure of Arginine Kinase McsB and McsA from Staphylococcus aureus
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 8gqd
Q-score: 0.359
Lu K, Luo B, Tao X, Li H, Xie Y, Zhao Z, Xia W, Su Z, Mao Z
To Be Published
- Mcsa-mcsb complex (Complex from Staphylococcus aureus)
- Protein-arginine kinase activator protein (6 kDa, Protein from Staphylococcus aureus)
- Protein-arginine kinase (38 kDa, Protein from Staphylococcus aureus)
- Zinc ion (65 Da, Ligand)
Cryo-EM structure of GPR34-Gi complex
Resolution: 3.27 Å
EM Method: Single-particle
Fitted PDBs: 8sai
Q-score: 0.471
Xia A, Yong X, Zhang C, Lin G, Jia G, Zhao C, Wang X, Hao Y, Wang Y, Zhou P, Yang X, Deng Y, Wu C, Chen Y, Zhu J, Tang X, Liu J, Zhang S, Zhang J, Xu Z, Hu Q, Zhao J, Yue Y, Yan W, Su Z, Wei Y, Zhou R, Dong H, Shao Z, Yang S
PNAS (2023) 120 pp. e2308435120-e2308435120 [ Pubmed: 37733739 DOI: doi:10.1073/pnas.2308435120 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Probable g-protein coupled receptor 34 (53 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Scfv16 (28 kDa, Protein from Mus musculus)
- Soluble cytochrome b562,probable g-protein coupled receptor 34, guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2, guanine nucleotide-binding protein g(i) subunit alpha-1, guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- O-[(s)-hydroxy{[(2s)-2-hydroxy-3-(octadec-9-enoyloxy)propyl]oxy}phosphoryl]-l-serine (523 Da, Ligand)
- Human gpr34 in complex with gi heterotrimer and scfv16 (Complex)
- Scfv16 (Complex from Mus musculus)
Streptococcus thermophilus Cas1-Cas2- prespacer ternary complex
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 8hi1
Q-score: 0.473
Tang D, Jia T, Luo Y, Mou B, Cheng J, Qi S, Yao S, Su Z, Yu Y, Chen Q
Innovation (NY) (2023) 4 pp. 100495-100495 [ Pubmed: 37663930 DOI: doi:10.1016/j.xinn.2023.100495 ]
- Streptococcus thermophilus cas1-cas2- prespacer ternary complex (Complex from Streptococcus thermophilus DGCC 7710)
- Crispr-associated endonuclease cas1 (35 kDa, Protein from Streptococcus thermophilus DGCC 7710)
- Dna (31-mer) (11 kDa, DNA from Phage #D)
- Dna (26-mer) (11 kDa, DNA from Phage #D)
- Type i-e crispr-associated endoribonuclease cas2 (13 kDa, Protein from Streptococcus thermophilus DGCC 7710)
