Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7xms
Q-score: 0.408
Zhao W, Han S, Qiu N, Feng W, Lu M, Zhang W, Wang M, Zhou Q, Chen S, Xu W, Du J, Chu X, Yi C, Dai A, Hu L, Shen MY, Sun Y, Zhang Q, Ma Y, Zhong W, Yang D, Wang MW, Wu B, Zhao Q
Cell Res (2022) 32 pp. 761-772 [ Pubmed: 35739238 DOI: doi:10.1038/s41422-022-00679-x ]
- Somatostatin receptor type 4 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Signle chain viable fragment of antibody (31 kDa, Protein from Mus musculus)
- Complex structure of somatostatin receptor 4 (sstr4) in complex with gi and its endogeneous ligand sst-14 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Somatostatin-14 (1 kDa, Protein from Homo sapiens)
CryoEM structure of somatostatin receptor 4 (SSTR4) with Gi1 and J-2156
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7xmt
Q-score: 0.424
Zhao W, Han S, Qiu N, Feng W, Lu M, Zhang W, Wang M, Zhou Q, Chen S, Xu W, Du J, Chu X, Yi C, Dai A, Hu L, Shen MY, Sun Y, Zhang Q, Ma Y, Zhong W, Yang D, Wang MW, Wu B, Zhao Q
Cell Res (2022) 32 pp. 761-772 [ Pubmed: 35739238 DOI: doi:10.1038/s41422-022-00679-x ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Single chain variable fragment of antibody (31 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- (2~{s})-2-[[(2~{s})-4-azanyl-2-[(4-methylnaphthalen-1-yl)sulfonylamino]butanoyl]amino]-3-phenyl-propanimidic acid (468 Da, Ligand)
- Somatostatin receptor type 4 (40 kDa, Protein from Homo sapiens)
- Complex structure of somatostatin receptor 4 (sstr4) with gi and j-2156 (Complex from Homo sapiens)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7bvc
Q-score: 0.564
Zhang L, Zhao Y, Gao Y, Wu L, Gao R, Zhang Q, Wang Y, Wu C, Wu F, Gurcha SS, Veerapen N, Batt SM, Zhao W, Qin L, Yang X, Wang M, Zhu Y, Zhang B, Bi L, Zhang X, Yang H, Guddat LW, Xu W, Wang Q, Li J, Besra GS, Rao Z
Science (2020) 368 pp. 1211-1219 [ Pubmed: 32327601 DOI: doi:10.1126/science.aba9102 ]
- Emba-embb (Complex from Mycolicibacterium smegmatis MC2 155)
- [(2z,6e,10e,14z,18e,22z,26z)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl] [(2s,3s,4s,5r)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl] hydrogen phosphate (911 Da, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Integral membrane indolylacetylinositol arabinosyltransferase embb (119 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Acpm (Complex from Mycolicibacterium smegmatis MC2 155)
- Integral membrane indolylacetylinositol arabinosyltransferase emba (116 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Meromycolate extension acyl carrier protein (10 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Calcium ion (40 Da, Ligand)
- 4'-phosphopantetheine (358 Da, Ligand)
- Mycobacterium smegmatis arabinosyltransferase emba-embb-acpm2 in complex with ethambutol (Complex)
- Phosphate ion (94 Da, Ligand)
- Ethambutol (204 Da, Ligand)
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 7bve
Q-score: 0.552
Zhang L, Zhao Y, Gao Y, Wu L, Gao R, Zhang Q, Wang Y, Wu C, Wu F, Gurcha SS, Veerapen N, Batt SM, Zhao W, Qin L, Yang X, Wang M, Zhu Y, Zhang B, Bi L, Zhang X, Yang H, Guddat LW, Xu W, Wang Q, Li J, Besra GS, Rao Z
Science (2020) 368 pp. 1211-1219 [ Pubmed: 32327601 DOI: doi:10.1126/science.aba9102 ]
- Embc (Complex from Mycolicibacterium smegmatis MC2 155)
- Meromycolate extension acyl carrier protein (10 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- N~3~-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-n-(2-sulfanylethyl)-beta-alaninamide (358 Da, Ligand)
- Acpm (Complex from Mycolicibacterium smegmatis MC2 155)
- Calcium ion (40 Da, Ligand)
- Mycobacterium smegmatis arabinosyltransferase embc2-acpm2 in complex with ethambutol (Complex)
- Phosphate ion (94 Da, Ligand)
- Ethambutol (204 Da, Ligand)
- Integral membrane indolylacetylinositol arabinosyltransferase embc (116 kDa, Protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155))
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 7bvf
Q-score: 0.58
Zhang L, Zhao Y, Gao Y, Wu L, Gao R, Zhang Q, Wang Y, Wu C, Wu F, Gurcha SS, Veerapen N, Batt SM, Zhao W, Qin L, Yang X, Wang M, Zhu Y, Zhang B, Bi L, Zhang X, Yang H, Guddat LW, Xu W, Wang Q, Li J, Besra GS, Rao Z
Science (2020) 368 pp. 1211-1219 [ Pubmed: 32327601 DOI: doi:10.1126/science.aba9102 ]
- Mycobacterium tuberculosis arabinosyltransferase emba-embb-acpm2 in complex with ethambutol (Complex)
- Emba and embb (Complex from Mycobacterium tuberculosis H37Rv)
- Cardiolipin (1 kDa, Ligand)
- Acpm (Complex from Mycolicibacterium smegmatis MC2 155)
- Meromycolate extension acyl carrier protein (10 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Calcium ion (40 Da, Ligand)
- Probable arabinosyltransferase a (116 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Ethambutol (204 Da, Ligand)
- Mono-trans, octa-cis decaprenyl-phosphate (779 Da, Ligand)
- Probable arabinosyltransferase b (120 kDa, Protein from Mycobacterium tuberculosis H37Rv)