Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7xms
Q-score: 0.408
Zhao W, Han S, Qiu N, Feng W, Lu M, Zhang W, Wang M, Zhou Q, Chen S, Xu W, Du J, Chu X, Yi C, Dai A, Hu L, Shen MY, Sun Y, Zhang Q, Ma Y, Zhong W, Yang D, Wang MW, Wu B, Zhao Q
Cell Res (2022) 32 pp. 761-772 [ Pubmed: 35739238 DOI: doi:10.1038/s41422-022-00679-x ]
- Somatostatin receptor type 4 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Signle chain viable fragment of antibody (31 kDa, Protein from Mus musculus)
- Complex structure of somatostatin receptor 4 (sstr4) in complex with gi and its endogeneous ligand sst-14 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Somatostatin-14 (1 kDa, Protein from Homo sapiens)
CryoEM structure of somatostatin receptor 4 (SSTR4) with Gi1 and J-2156
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7xmt
Q-score: 0.424
Zhao W, Han S, Qiu N, Feng W, Lu M, Zhang W, Wang M, Zhou Q, Chen S, Xu W, Du J, Chu X, Yi C, Dai A, Hu L, Shen MY, Sun Y, Zhang Q, Ma Y, Zhong W, Yang D, Wang MW, Wu B, Zhao Q
Cell Res (2022) 32 pp. 761-772 [ Pubmed: 35739238 DOI: doi:10.1038/s41422-022-00679-x ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Single chain variable fragment of antibody (31 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- (2~{s})-2-[[(2~{s})-4-azanyl-2-[(4-methylnaphthalen-1-yl)sulfonylamino]butanoyl]amino]-3-phenyl-propanimidic acid (468 Da, Ligand)
- Somatostatin receptor type 4 (40 kDa, Protein from Homo sapiens)
- Complex structure of somatostatin receptor 4 (sstr4) with gi and j-2156 (Complex from Homo sapiens)
Cryo-EM structure of the adhesion GPCR ADGRD1 in complex with miniGs
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7wu2
Q-score: 0.53
Qu X, Qiu N, Wang M, Zhang B, Du J, Zhong Z, Xu W, Chu X, Ma L, Yi C, Han S, Shui W, Zhao Q, Wu B
Nature (2022) 604 pp. 779-785 [ DOI: doi:10.1038/s41586-022-04580-w Pubmed: 35418679 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- The adhesion gpcr adgrd1 in complex with minigs (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Nanobody nb35 (17 kDa, Protein from Lama glama)
- Adhesion g-protein coupled receptor d1 (38 kDa, Protein from Homo sapiens)
- Nanobody nb35 (Complex from Lama glama)