COVID-19 RNA-dependent RNA polymerase post-translocated catalytic complex
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 7bzf
Q-score: 0.47
Wang Q, Wu J, Wang H, Gao Y, Liu Q, Mu A, Ji W, Yan L, Zhu Y, Zhu C, Fang X, Yang X, Huang Y, Gao H, Liu F, Ge J, Sun Q, Yang X, Xu W, Liu Z, Yang H, Lou Z, Jiang B, Guddat LW, Gong P, Rao Z
Cell (2020) 182 pp. 417-428.e13 [ DOI: doi:10.1016/j.cell.2020.05.034 Pubmed: 32526208 ]
- Structure of covid-19 rna-dependent rna polymerase in complex with rna (155 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Rna (5'-r(*up*gp*up*up*cp*gp*ap*cp*gp*ap*cp*ap*cp*a)-3') (4 kDa, RNA from Foot-and-mouth disease virus)
- Non-structural protein 8 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rna (31-mer) (10 kDa, RNA from Foot-and-mouth disease virus)
- Non-structural protein 7 (9 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Rna-directed rna polymerase (108 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
COVID-19 RNA-dependent RNA polymerase pre-translocated catalytic complex
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 7c2k
Q-score: 0.581
Wang Q, Wu J, Wang H, Gao Y, Liu Q, Mu A, Ji W, Yan L, Zhu Y, Zhu C, Fang X, Yang X, Huang Y, Gao H, Liu F, Ge J, Sun Q, Yang X, Xu W, Liu Z, Yang H, Lou Z, Jiang B, Guddat LW, Gong P, Rao Z
Cell (2020) 182 pp. 417-428.e13 [ Pubmed: 32526208 DOI: doi:10.1016/j.cell.2020.05.034 ]
- Non-structural protein 7 (9 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rna (5'-r(*up*gp*up*up*cp*gp*ap*cp*gp*ap*cp*ap*cp*ap*gp*g*(f86)p*g)-3') (5 kDa, RNA from Foot-and-mouth disease virus)
- Covid-19 rna-dependent rna polymerase pre-translocated catalytic complex (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rna (29-mer) (9 kDa, RNA from Foot-and-mouth disease virus)
- Rna-directed rna polymerase (108 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 8 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
COVID-19 RNA-dependent RNA polymerase pre-translocated catalytic complex in conformation I
Wang Q, Wu J, Wang H, Gao Y, Liu Q, Mu A, Ji W, Yan L, Zhu Y, Zhu C, Fang X, Yang X, Huang Y, Gao H, Liu F, Ge J, Sun Q, Yang X, Xu W, Liu Z, Yang H, Lou Z, Jiang B, Guddat LW, Gong P, Rao Z
Cell (2020) 182 pp. 417-428.e13 [ DOI: doi:10.1016/j.cell.2020.05.034 Pubmed: 32526208 ]
- Rna-directed rna polymerase (Protein from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 8 (Protein from Severe acute respiratory syndrome coronavirus 2)
- Rna (5'-r(p*gp*gp*gp*ap*gp*cp*up*cp*cp*up*cp*cp*up*gp*up*gp*up*cp*gp*u)-3') (RNA from Foot-and-mouth disease virus)
- Rna (5'-r(p*ap*cp*gp*ap*cp*ap*cp*ap*gp*g*(gs4)p*g)-3') (RNA from Foot-and-mouth disease virus)
- Non-structural protein 7 (Protein from Severe acute respiratory syndrome coronavirus 2)
- Covid-19 rna-dependent rna polymerase pre-translocated catalytic complex in conformation i (150 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
COVID-19 RNA-dependent RNA polymerase pre-translocated catalytic complex in conformation II
Wang Q, Wu J, Wang H, Gao Y, Liu Q, Mu A, Ji W, Yan L, Zhu Y, Zhu C, Fang X, Yang X, Huang Y, Gao H, Liu F, Ge J, Sun Q, Yang X, Xu W, Liu Z, Yang H, Lou Z, Jiang B, Guddat LW, Gong P, Rao Z
Cell (2020) 182 pp. 417-428.e13 [ DOI: doi:10.1016/j.cell.2020.05.034 Pubmed: 32526208 ]
- Rna-directed rna polymerase (Protein from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 8 (Protein from Severe acute respiratory syndrome coronavirus 2)
- Rna (5'-r(p*gp*gp*gp*ap*gp*cp*up*cp*cp*up*cp*cp*up*gp*up*gp*up*cp*gp*u)-3') (RNA from Foot-and-mouth disease virus)
- Rna (5'-r(p*ap*cp*gp*ap*cp*ap*cp*ap*gp*g*(gs4)p*g)-3') (RNA from Foot-and-mouth disease virus)
- Covid-19 rna-dependent rna polymerase pre-translocated catalytic complex in conformation ii (Complex from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 7 (Protein from Severe acute respiratory syndrome coronavirus 2)