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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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dna/ polymerase AND author_name:"Ren Y" AND sample_type:"complex" AND database:"EMDB" AND author_name:"Hou H"

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EMD-35712

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human RNA polymerase III pre-initiation complex closed DNA 1

Release date: June 7, 2023
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8ity
Q-score: 0.291

Hou H, Jin Q, Ren Y, Chen Z, Wang Q, Xu Y

Cell Res (2023) 33 pp. 565-568 [ DOI: doi:10.1038/s41422-023-00819-x Pubmed: 37165065 ]

Sample:

Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
Dna (Complex)
Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
Dna (82-mer) (143 kDa, DNA from Homo sapiens)
Transcription factor iiib 50 kda subunit (46 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
Snrna-activating protein complex subunit 3 (46 kDa, Protein from Homo sapiens)
Rna polymerase iii pre-initiation complex closed complex 1 (Complex)
Dna-directed rna polymerase iii subunit rpc4 (35 kDa, Protein from Homo sapiens)
Dna (82-mer) (143 kDa, DNA from Homo sapiens)
Magnesium ion (24 Da, Ligand)
Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
Snrna-activating protein complex subunit 1 (43 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
Snrna-activating protein complex subunit 4 (159 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
Iron/sulfur cluster (351 Da, Ligand)
Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
Transcription factor tfiiib component b'' homolog (294 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Rna polymerase iii pre-initiation complex closed complex 1 (1 MDa, Complex from Homo sapiens)
Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)

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EMD-35719

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RNA polymerase III pre-initiation complex melting complex 1

Release date: May 24, 2023
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8iue
Q-score: 0.291

Hou H, Jin Q, Ren Y, Chen Z, Wang Q, Xu Y

Cell Res (2023) 33 pp. 565-568 [ DOI: doi:10.1038/s41422-023-00819-x Pubmed: 37165065 ]

Sample:

Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
Dna (Complex)
Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
Transcription factor iiib 50 kda subunit (46 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
Snrna-activating protein complex subunit 3 (46 kDa, Protein from Homo sapiens)
Human gene for u 6 rna (143 kDa, DNA from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc4 (35 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
Dna (74-mer) (143 kDa, DNA from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
Snrna-activating protein complex subunit 1 (43 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
Snrna-activating protein complex subunit 4 (159 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
Iron/sulfur cluster (351 Da, Ligand)
Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase (Complex)
Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
Rna polymerase iii pre-initiation complex melting complex 1 (1 MDa, Complex from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
Transcription factor tfiiib component b'' homolog (294 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Transcription factor (Complex)
Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)

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EMD-35722

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RNA polymerase III pre-initiation complex open complex 1

Release date: May 24, 2023
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8iuh
Q-score: 0.341

Hou H, Jin Q, Ren Y, Chen Z, Wang Q, Xu Y

Cell Res (2023) 33 pp. 565-568 [ DOI: doi:10.1038/s41422-023-00819-x Pubmed: 37165065 ]

Sample:

Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
Dna (Complex)
Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
Transcription factor iiib 50 kda subunit (46 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
Snrna-activating protein complex subunit 3 (46 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii, snapc (Complex)
Dna-directed rna polymerase iii subunit rpc4 (35 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
Snrna-activating protein complex subunit 1 (43 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
Snrna-activating protein complex subunit 4 (159 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
Iron/sulfur cluster (351 Da, Ligand)
Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
Dna (81-mer) (143 kDa, DNA from Homo sapiens)
Dna (81-mer) (143 kDa, DNA from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
Transcription factor tfiiib component b'' homolog (294 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Tfiiib (Complex)
Rna polymerase iii pre-initiation complex closed complex 1 (1 MDa, Complex from Homo sapiens)
Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)

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EMD-30779

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Structure of Human RNA Polymerase III elongation complex

Release date: March 17, 2021
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7dn3
Q-score: 0.307

Li L, Yu Z, Zhao D, Ren Y, Hou H, Xu Y

Cell Res (2021) 31 pp. 791-800 [ Pubmed: 33674783 DOI: doi:10.1038/s41422-021-00472-2 ]

Sample:

Rna polymerase iii elongation (Complex from Homo sapiens)
Structure of human rna polymerase iii elongation complex (Complex from Homo sapiens)
Dna (Complex from Homo sapiens)
Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
Dna (5'-d(p*tp*cp*gp*tp*cp*tp*gp*ap*tp*cp*tp*cp*gp*gp*ap*a)-3') (4 kDa, DNA from Homo sapiens)
Rna (Complex)
Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc4 (44 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
Rna (5'-r(p*cp*cp*cp*gp*ap*u)-3') (1 kDa, RNA from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
Dna (5'-d(p*tp*tp*cp*cp*gp*ap*gp*ap*tp*cp*ap*gp*ap*cp*gp*ap*gp*ap*tp*cp*gp*gp*g)-3') (7 kDa, DNA from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
Iron/sulfur cluster (351 Da, Ligand)
Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)

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EMD-30865

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RNA polymerase III EC complex in post-translocation state

Release date: March 17, 2021
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 7du2
Q-score: 0.389

Li L, Yu Z, Zhao D, Ren Y, Hou H, Xu Y

Cell Res (2021) 31 pp. 791-800 [ Pubmed: 33674783 DOI: doi:10.1038/s41422-021-00472-2 ]

Sample:

Rna polymerase iii elongation (Complex from Homo sapiens)
Rna (5'-r(p*ap*up*c)-3') (895 Da, RNA from Homo sapiens)
Dna (Complex from Homo sapiens)
Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
Rna (Complex)
Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
Dna (5'-d(p*gp*tp*cp*tp*gp*ap*tp*cp*tp*cp*gp*gp*ap*a)-3') (4 kDa, DNA from Homo sapiens)
Dna (5'-d(p*tp*tp*cp*cp*gp*ap*gp*ap*tp*cp*ap*gp*ap*cp*gp*ap*gp*ap*t)-3') (5 kDa, DNA from Homo sapiens)
Zinc ion (65 Da, Ligand)
Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc4 (44 kDa, Protein from Homo sapiens)
Structure of human rna polymerase iii elongation complex (Complex from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
Iron/sulfur cluster (351 Da, Ligand)
Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)

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Display: Statistics

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Select database:

EMDB [5]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

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Field: