EMDB < Search results

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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dna/ polymerase AND author_orcid:"0000-0003-2545-4319" AND resolution:[3 TO 4} AND xref_links:"alphafold" AND xref_links:"pfam" AND author_orcid:"0000-0002-7785-4384" AND release_date:[2019-01-01T00:00:00Z TO 2019-12-31T23:59:59Z]

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EMD-10539

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Processive human polymerase delta holoenzyme

Release date: Dec. 18, 2019
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 6tny
Q-score: 0.442

Lancey C, Tehseen M, Raducanu VS, Rashid F, Merino N, Ragan TJ, Savva CG, Zaher MS, Shirbini A, Blanco FJ, Hamdan SM, De Biasio A

Nat Commun (2020) 11 pp. 1109-1109 [ Pubmed: 32111820 DOI: doi:10.1038/s41467-020-14898-6 ]

Sample:

Proliferating cell nuclear antigen (29 kDa, Protein from Homo sapiens)
Dna primer (7 kDa, DNA from synthetic construct)
Iron/sulfur cluster (351 Da, Ligand)
Dna primer, template (Complex from synthetic construct)
Dna polymerase delta subunit 3 (52 kDa, Protein from Homo sapiens)
Dna polymerase delta subunit 2 (51 kDa, Protein from Homo sapiens)
Dna polymerase delta subunit 4 (16 kDa, Protein from Homo sapiens)
Toolbelt (Complex)
Thymidine-5'-triphosphate (482 Da, Ligand)
Zinc ion (65 Da, Ligand)
Dna template (11 kDa, DNA from synthetic construct)
Dna polymerase (Complex from Homo sapiens)
Proliferating cell nuclear antigen (Complex from Homo sapiens)
Dna polymerase delta catalytic subunit (123 kDa, Protein from Homo sapiens)

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