catalytic core of human telomerase holoenzyme
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 7v99
Q-score: 0.247
Wan F, Ding Y, Zhang Y, Wu Z, Li S, Yang L, Yan X, Lan P, Li G, Wu J, Lei M
Cell Res (2021) 31 pp. 1275-1290 [ Pubmed: 34782750 DOI: doi:10.1038/s41422-021-00586-7 ]
- Primer dna (7 kDa, DNA from Homo sapiens)
- Histone h2a type 1-b/e (14 kDa, Protein from Human)
- Histone h2b type 1-k (13 kDa, Protein from Human)
- Catalytic core (Complex from Homo sapiens)
- Telomerase rna component (145 kDa, RNA from Human)
- Telomerase reverse transcriptase (127 kDa, Protein from Human)
Structure of Human RNA Polymerase III elongation complex
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7dn3
Q-score: 0.307
Li L, Yu Z, Zhao D, Ren Y, Hou H, Xu Y
Cell Res (2021) 31 pp. 791-800 [ Pubmed: 33674783 DOI: doi:10.1038/s41422-021-00472-2 ]
- Rna polymerase iii elongation (Complex from Homo sapiens)
- Structure of human rna polymerase iii elongation complex (Complex from Homo sapiens)
- Dna (Complex from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Dna (5'-d(p*tp*cp*gp*tp*cp*tp*gp*ap*tp*cp*tp*cp*gp*gp*ap*a)-3') (4 kDa, DNA from Homo sapiens)
- Rna (Complex)
- Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc4 (44 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
- Rna (5'-r(p*cp*cp*cp*gp*ap*u)-3') (1 kDa, RNA from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
- Dna (5'-d(p*tp*tp*cp*cp*gp*ap*gp*ap*tp*cp*ap*gp*ap*cp*gp*ap*gp*ap*tp*cp*gp*gp*g)-3') (7 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Iron/sulfur cluster (351 Da, Ligand)
- Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)