Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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hemagglutinin* AND film_detector_model:"GATAN K3 (6K X 4K)" AND software_ft:"CTFFIND" AND author_orcid:"0000-0002-3087-8397"

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EMD-23098

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Cryo-EM structure of the VRC316 clinical trial, vaccine-elicited, human antibody 316-310-1B11 in complex with an H2 CAN05 HA trimer

Release date: Nov. 3, 2021
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 7l0l
Q-score: 0.555

Andrews SF, Raab JE, Gorman J, Gillespie RA, Cheung CSF, Rawi R, Cominsky LY, Boyington JC, Creanga A, Shen CH, Harris DR, Olia AS, Nazzari AF, Zhou T, Houser KV, Chen GL, Mascola JR, Graham BS, Kanekiyo M, Ledgerwood JE, Kwong PD, McDermott AB

Nat Med (2022) 28 pp. 373-382 [ Pubmed: 35115707 DOI: doi:10.1038/s41591-021-01636-8 ]

Sample:

2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Hemagglutinin ha2 chain (25 kDa, Protein from Influenza A virus (A/Canada/720/2005(H2N2)))
316-310-1b11 fab in complex with an h2 can05 ha trimer (Complex from Influenza A virus)
316-310-1b11 light chain (23 kDa, Protein from Homo sapiens)
Hemagglutinin ha1 chain (38 kDa, Protein from Influenza A virus (A/Canada/720/2005(H2N2)))
316-310-1b11 heavy chain (25 kDa, Protein from Homo sapiens)

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