Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ Pubmed: 34376662 DOI: doi:10.1038/s41467-021-25087-4 ]
BG505 SOSIP reconstructed from a designed nanoparticle, BG505 SOSIP-T33-31 (Component A)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7l7t
Q-score: 0.428
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ DOI: doi:10.1038/s41467-021-25087-4 Pubmed: 34376662 ]
- Bg505 sosip.v5.2(7s) - gp120 (56 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip.v5.2(7s) - gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosip reconstructed from a designed nanoparticle, bg505 sosip-t33-31 (component a) (Complex from Human immunodeficiency virus 1)
BG505 SOSIP reconstructed from a designed nanoparticle, BG505 SOSIP-T33-31 (Component B)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7l7u
Q-score: 0.439
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ Pubmed: 34376662 DOI: doi:10.1038/s41467-021-25087-4 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosip.v5.2(7s) - gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip reconstructed from a designed nanoparticle, bg505 sosip-t33-31 (component b) (Complex from Human immunodeficiency virus 1)
- Bg505 sosip.v5.2(7s) - gp120 (56 kDa, Protein from Human immunodeficiency virus 1)
Designed tetrahedral nanoparticle T33-31 presenting BG505 SOSIP trimers
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7l85
Q-score: 0.589
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ Pubmed: 34376662 DOI: doi:10.1038/s41467-021-25087-4 ]
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-1 from animal Rh.32034 (Wk26 time point)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7l86
Q-score: 0.504
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ Pubmed: 34376662 DOI: doi:10.1038/s41467-021-25087-4 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosip md39 in complex with the polyclonal fab pabc-1 from animal rh.32034 (wk26 time point) (Complex)
- Bg505 sosip md39 gp120/gp41 (Complex from Human immunodeficiency virus 1)
- Rh.32034 pabc-1 - heavy chain (10 kDa, Protein from Macaca mulatta)
- Bg505 sosip md39 - gp120 (55 kDa, Protein from Human immunodeficiency virus 1)
- Polyclonal fab pabc-1 from animal rh.32034 (Complex from Macaca mulatta)
- Rh.32034 pabc-1 - light chain (8 kDa, Protein from Macaca mulatta)
- Bg505 sosip md39 - gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-2 from animal Rh.32034 (Wk26 time point)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7l87
Q-score: 0.47
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ Pubmed: 34376662 DOI: doi:10.1038/s41467-021-25087-4 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Polyclonal fab pabc-2 from animal rh.32034 (Complex from Macaca mulatta)
- Bg505 sosip md39 - gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip md39 gp120/gp41 (Complex from Human immunodeficiency virus 1)
- Rh.32034 pabc-2 - light chain (8 kDa, Protein from Macaca mulatta)
- Rh.32034 pabc-2 - heavy chain (10 kDa, Protein from Macaca mulatta)
- Bg505 sosip md39 in complex with the polyclonal fab pabc-2 from animal rh.32034 (wk26 time point) (Complex)
- Bg505 sosip md39 - gp120 (55 kDa, Protein from Human immunodeficiency virus 1)
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-3 from animal Rh.32034 (Wk26 time point)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7l88
Q-score: 0.47
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ Pubmed: 34376662 DOI: doi:10.1038/s41467-021-25087-4 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rh.32034 pabc-3 - heavy chain (9 kDa, Protein from Macaca mulatta)
- Bg505 sosip md39 gp120/gp41 (Complex from Human immunodeficiency virus 1)
- Rh.32034 pabc-3 - light chain (9 kDa, Protein from Macaca mulatta)
- Bg505 sosip md39 in complex with the polyclonal fab pabc-3 from animal rh.32034 (wk26 time point) (Complex)
- Polyclonal fab pabc-3 from animal rh.32034 (Complex from Macaca mulatta)
- Bg505 sosip md39 - gp120 (55 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip md39 - gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-4 from animal Rh.32034 (Wk26 time point)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7l89
Q-score: 0.47
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ DOI: doi:10.1038/s41467-021-25087-4 Pubmed: 34376662 ]
- Rh.32034 pabc-4 - light chain (8 kDa, Protein from Macaca mulatta)
- Bg505 sosip md39 in complex with the polyclonal fab pabc-4 from animal rh.32034 (wk26 time point) (Complex)
- Polyclonal fab pabc-4 from animal rh.32034 (Complex from Macaca mulatta)
- Rh.32034 pabc-4 - heavy chain (9 kDa, Protein from Macaca mulatta)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosip md39 bg505 sosip md39 gp120/gp41 (Complex from Human immunodeficiency virus 1)
- Bg505 sosip md39 - gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip md39 - gp120 (55 kDa, Protein from Human immunodeficiency virus 1)
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-1 from animal Rh.33104 (Wk26 time point)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7l8a
Q-score: 0.524
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ Pubmed: 34376662 DOI: doi:10.1038/s41467-021-25087-4 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosip md39 - gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- Rh.33104 pabc-1 - light chain (8 kDa, Protein from Macaca mulatta)
- Rh.33104 pabc-1 - heavy chain (9 kDa, Protein from Macaca mulatta)
- Bg505 sosip md39 - gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip md39 in complex with the polyclonal fab pabc-1 from animal rh.33104 (wk26 time point) (Complex from Human immunodeficiency virus 1)
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-2 from animal Rh.33104 (Wk26 time point)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7l8b
Q-score: 0.466
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ Pubmed: 34376662 DOI: doi:10.1038/s41467-021-25087-4 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosip md39 - gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip md39 - gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip md39 in complex with the polyclonal fab pabc-2 from animal rh.33104 (wk26 time point) (Complex from Human immunodeficiency virus 1)
- Rh.33104 pabc-2 - heavy chain (10 kDa, Protein from Macaca mulatta)
- Rh.33104 pabc-2 - light chain (9 kDa, Protein from Macaca mulatta)