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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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initial_angle_assignment_type:"MAXIMUM LIKELIHOOD" AND author_name:"Wang P" AND assembly_molecular_weight:{500000 TO 1000000] AND film_detector_model:"GATAN K2 SUMMIT (4K X 4K)" AND natural_source_ncbi_code:"9606"

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EMD-9945

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Intact human mitochondrial calcium uniporter complex with MICU1/MICU2 subunits

Release date: Sept. 9, 2020
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6k7y
Q-score: 0.511

Zhuo W, Zhou H, Guo R, Yi J, Zhang L, Yu L, Sui Y, Zeng W, Wang P, Yang M

Protein Cell (2021) 12 pp. 220-229 [ DOI: doi:10.1007/s13238-020-00776-w Pubmed: 32862359 ]

Sample:

Cardiolipin (1 kDa, Ligand)
(9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
Intact human mitochondrial calcium uniporter complex with micu1/micu2 subunits (Complex from Homo sapiens)
Calcium uniporter protein, mitochondrial (32 kDa, Protein from Homo sapiens)
Calcium uptake protein 1, mitochondrial (54 kDa, Protein from Homo sapiens)
Calcium ion (40 Da, Ligand)
Essential mcu regulator, mitochondrial (5 kDa, Protein from Homo sapiens)
Calcium uptake protein 2, mitochondrial (39 kDa, Protein from Homo sapiens)

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