Cryo-EM structure of Mycobacterium tuberculosis irtAB in complex with an AMP-PNP
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 7wiv
Q-score: 0.577
Sun S, Gao Y, Yang X, Yang X, Hu T, Liang J, Xiong Z, Ran Y, Ren P, Bai F, Guddat LW, Yang H, Rao Z, Zhang B
Protein Cell (2023) 14 pp. 448-458 [ Pubmed: 36882106 DOI: doi:10.1093/procel/pwac060 ]
- Irtab (Complex from Mycobacterium tuberculosis H37Rv)
- Mycobactin import atp-binding/permease protein irta (93 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Mycobactin import atp-binding/permease protein irtb (61 kDa, Protein from Mycobacterium tuberculosis H37Rv)
Cryo-EM structure of Mycobacterium tuberculosis irtAB complexed with ATP in an occluded conformation
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 7wiw
Q-score: 0.56
Sun S, Gao Y, Yang X, Yang X, Hu T, Liang J, Xiong Z, Ran Y, Ren P, Bai F, Guddat LW, Yang H, Rao Z, Zhang B
Protein Cell (2023) 14 pp. 448-458 [ Pubmed: 36882106 DOI: doi:10.1093/procel/pwac060 ]
- Irtab (Complex from Mycobacterium tuberculosis H37Rv)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Mycobactin import atp-binding/permease protein irtb (61 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Magnesium ion (24 Da, Ligand)
- Mycobactin import atp-binding/permease protein irta (93 kDa, Protein from Mycobacterium tuberculosis H37Rv)
Cryo-EM structure of Mycobacterium tuberculosis irtAB in complex with ADP
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 7wix
Q-score: 0.48
Sun S, Gao Y, Yang X, Yang X, Hu T, Liang J, Xiong Z, Ran Y, Ren P, Bai F, Guddat LW, Yang H, Rao Z, Zhang B
Protein Cell (2023) 14 pp. 448-458 [ Pubmed: 36882106 DOI: doi:10.1093/procel/pwac060 ]
- Irtab (Complex from Mycobacterium tuberculosis H37Rv)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Mycobactin import atp-binding/permease protein irta (93 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Mycobactin import atp-binding/permease protein irtb (61 kDa, Protein from Mycobacterium tuberculosis H37Rv)
Mycobacterium smegmatis Sdh1 in complex with UQ1
Resolution: 2.53 Å
EM Method: Single-particle
Fitted PDBs: 7d6v
Q-score: 0.636
Zhou X, Gao Y, Wang W, Yang X, Yang X, Liu F, Tang Y, Lam SM, Shui G, Yu L, Tian C, Guddat LW, Wang Q, Rao Z, Gong H
PNAS (2021) 118 [ Pubmed: 33876763 DOI: doi:10.1073/pnas.2022308118 ]
- Iron/sulfur cluster (351 Da, Ligand)
- Fe3-s4 cluster (295 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Fumarate reductase iron-sulfur subunit (28 kDa, Protein from Mycolicibacterium smegmatis)
- (1s)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate (720 Da, Ligand)
- Flavin-adenine dinucleotide (785 Da, Ligand)
- Succinate dehydrogenase subunit a (70 kDa, Protein from Mycolicibacterium smegmatis)
- Mycobacterium smegmatis sdh1 in complex with uq1 (Complex from Mycolicibacterium smegmatis MC2 51)
- Ubiquinone-1 (250 Da, Ligand)
- Succinate dehydrogenase (membrane anchor subunit) (32 kDa, Protein from Mycolicibacterium smegmatis)
Mycobacterium smegmatis Sdh1 complex in the apo form
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 7d6x
Q-score: 0.587
Zhou X, Gao Y, Wang W, Yang X, Yang X, Liu F, Tang Y, Lam SM, Shui G, Yu L, Tian C, Guddat LW, Wang Q, Rao Z, Gong H
PNAS (2021) 118 [ Pubmed: 33876763 DOI: doi:10.1073/pnas.2022308118 ]
- Iron/sulfur cluster (351 Da, Ligand)
- Fe3-s4 cluster (295 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Fumarate reductase iron-sulfur subunit (28 kDa, Protein from Mycolicibacterium smegmatis)
- Mycobacterium smegmatis sdh1 complex in apo form (Complex from Mycolicibacterium smegmatis MC2 51)
- (1s)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate (720 Da, Ligand)
- Flavin-adenine dinucleotide (785 Da, Ligand)
- Succinate dehydrogenase subunit a (70 kDa, Protein from Mycolicibacterium smegmatis)
- Succinate dehydrogenase (membrane anchor subunit) (32 kDa, Protein from Mycolicibacterium smegmatis)