EMDB < Search results

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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initial_angle_assignment_type:"MAXIMUM LIKELIHOOD" AND xref_links:"pdb" AND assembly_molecular_weight:{100000 TO 250000] AND author_orcid:"0000-0002-5593-4682" AND release_date:[2024-01-01T00:00:00Z TO 2024-12-31T23:59:59Z]

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EMD-18343

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Apo Hantaan virus polymerase in monomeric state

Release date: March 27, 2024
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8qe5
Q-score: 0.625

Durieux Trouilleton Q, Housset D, Tarillon P, Arragain B, Malet H

Nat Commun (2024) 15 pp. 2256-2256 [ Pubmed: 38480734 DOI: doi:10.1038/s41467-024-46601-4 ]

Sample:

Hantaan virus polymerase (250 kDa, Complex from Hantaan virus 76-118)
Rna-directed rna polymerase l (249 kDa, Protein from Hantaan virus 76-118)

EMD-17865

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Tilapia Lake Virus polymerase in vRNA elongation state with additional mode B promoter (transcriptase conformation)

Release date: Jan. 10, 2024
Resolution: 2.42 Å
EM Method: Single-particle
Fitted PDBs: 8psz
Q-score: 0.647

Arragain B, Pelosse M, Thompson A, Cusack S

Nat Commun (2023) 14 pp. 8145-8145 [ DOI: doi:10.1038/s41467-023-44044-x Pubmed: 38066000 ]

Sample:

Polymerase acidic protein (pa-like) (47 kDa, Protein from Tilapia lake virus)
[(2~{r},3~{s},4~{r},5~{r})-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-~{n}-[oxidanyl(phosphonooxy)phosphoryl]phosphonamidic acid (482 Da, Ligand)
5' vrna end - vrna loop (40-mer) (12 kDa, RNA from Tilapia lake virus)
Magnesium ion (24 Da, Ligand)
Tilapia lake virus polymerase (Complex from Tilapia lake virus)
Water (18 Da, Ligand)
Rna-dependent rna polymerase (53 kDa, Protein from Tilapia lake virus)
Zinc ion (65 Da, Ligand)
Transcription-like product (6 kDa, RNA from Tilapia lake virus)
Putative pb1 (57 kDa, Protein from Tilapia lake virus)

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