Resolution: 2.99 Å
EM Method: Single-particle
Fitted PDBs: 8u4v
Q-score: 0.572
Erramilli SK, Dominik PK, Ogbu CP, Kossiakoff AA, Vecchio AJ
Commun Biol (2024) 7 pp. 733- [ DOI: doi:10.1038/s42003-024-06437-6 ]
- Cop-1 sfab light chain (23 kDa, Protein from Homo sapiens)
- Claudin-4 (22 kDa, Protein from Homo sapiens)
- Heat-labile enterotoxin b chain (14 kDa, Protein from Clostridium perfringens)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Water (18 Da, Ligand)
- Human claudin-4 complex with clostridium perfringens enterotoxin c-terminal domain, sfab cop-1, and nanobody (100 kDa, Complex from Homo sapiens)
- Cop-1 sfab heavy chain (28 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (13 kDa, Protein from synthetic construct)
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 7php
Q-score: 0.505
Bloch JS, Mukherjee S, Kowal J, Filippova EV, Niederer M, Pardon E, Steyaert J, Kossiakoff AA, Locher KP
PNAS (2021) 118 [ DOI: doi:10.1073/pnas.2115435118 Pubmed: 34782475 ]
- Multidrug resistance protein norm (52 kDa, Protein from Vibrio cholerae RC385)
- Norm-nb17_4 (14 kDa, Protein from synthetic construct)
- Water (18 Da, Ligand)
- Nabfab lc (23 kDa, Protein from synthetic construct)
- Nabfab hc (25 kDa, Protein from synthetic construct)
- Complex of vibrio cholerae mate transporter norm, chimeric nanobody norm-nb17_4, nabfab, and anti-fab nanobody (Complex from Vibrio cholerae RC385)
- Anti-fab nanobody (13 kDa, Protein from Lama glama)
Resolution: 8.45 Å
EM Method: Single-particle
Fitted PDBs: 7phq
Q-score: 0.111
Bloch JS, Mukherjee S, Kowal J, Filippova EV, Niederer M, Pardon E, Steyaert J, Kossiakoff AA, Locher KP
PNAS (2021) 118 [ DOI: doi:10.1073/pnas.2115435118 Pubmed: 34782475 ]
- Divalent metal cation transporter mnth (47 kDa, Protein from Staphylococcus capitis)
- Water (18 Da, Ligand)
- Complex of staphylococcus capitis divalent metal ion transporter (dmt), chimeric nanobody dmtnb16_4, nabfab, and anti-fab nanobody (Complex from synthetic construct)
- Nabfab lc (23 kDa, Protein from synthetic construct)
- Nabfab hc (25 kDa, Protein from synthetic construct)
- Dmt-nb16_4 (14 kDa, Protein from synthetic construct)
- Anti-fab nanobody (13 kDa, Protein from Lama glama)
Resolution: 3.78 Å
EM Method: Single-particle
Fitted PDBs: 7pij
Q-score: 0.422
Bloch JS, Mukherjee S, Kowal J, Filippova EV, Niederer M, Pardon E, Steyaert J, Kossiakoff AA, Locher KP
PNAS (2021) 118 [ DOI: doi:10.1073/pnas.2115435118 Pubmed: 34782475 ]
- Divalent metal cation transporter mnth (47 kDa, Protein from Staphylococcus capitis)
- Dmtnb16_4 (14 kDa, Protein from synthetic construct)
- Water (18 Da, Ligand)
- Complex of staphylococcus capitis divalent metal ion transporter (dmt), chimeric nanobody dmtnb16_4, nabfab, and anti-fab nanobody (Complex from synthetic construct)
- Nabfab lc (23 kDa, Protein from synthetic construct)
- Nabfab hc (25 kDa, Protein from synthetic construct)
- Anti-fab nanobody (13 kDa, Protein from Lama glama)