Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6a90
Q-score: 0.56
Shen H, Li Z, Jiang Y, Pan X, Wu J, Cristofori-Armstrong B, Smith JJ, Chin YKY, Lei J, Zhou Q, King GF, Yan N
Science (2018) 362 [ DOI: doi:10.1126/science.aau2596 Pubmed: 30049784 ]
- Dc1a (Complex from Diguetia canities)
- Complex of voltage-gated sodium channel navpas from american cockroach periplaneta americana and dc1a (200 kDa, Complex)
- Sodium channel protein pafpc1 (183 kDa, Protein from Periplaneta americana)
- N-acetyl-d-glucosamine (221 Da, Ligand)
- Voltage-gated sodium channel navpas from american cockroach periplaneta americana (Complex from Periplaneta americana)
- Mu-diguetoxin-dc1a (6 kDa, Protein from Diguetia canities)
- Sodium ion (22 Da, Ligand)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6a91
Q-score: 0.515
Shen H, Li Z, Jiang Y, Pan X, Wu J, Cristofori-Armstrong B, Smith JJ, Chin YKY, Lei J, Zhou Q, King GF, Yan N
Science (2018) 362 [ Pubmed: 30049784 DOI: doi:10.1126/science.aau2596 ]
- Complex of voltage-gated sodium channel navpas from american cockroach periplaneta americana bound with saxitoxin and dc1a (200 kDa, Complex)
- Dc1a (Complex from Diguetia canities)
- Voltage-gated sodium channel navpas from american cockroach periplaneta americana (Complex from Periplaneta americana)
- N-acetyl-d-glucosamine (221 Da, Ligand)
- [(3as,4r,10as)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3h,8h-pyrrolo[1,2-c]purin-4-yl]methyl carbamate (299 Da, Ligand)
- Sodium channel protein pafpc1 (183 kDa, Protein from Periplaneta americana)
- Mu-diguetoxin-dc1a (6 kDa, Protein from Diguetia canities)
- Water (18 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 6a95
Q-score: 0.565
Shen H, Li Z, Jiang Y, Pan X, Wu J, Cristofori-Armstrong B, Smith JJ, Chin YKY, Lei J, Zhou Q, King GF, Yan N
Science (2018) 362 [ Pubmed: 30049784 DOI: doi:10.1126/science.aau2596 ]
- Complex of voltage-gated sodium channel navpas from american cockroach periplaneta americana bound with saxitoxin and dc1a (200 kDa, Complex)
- (1r,5r,6r,7r,9s,11s,12s,13s,14s)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol (non-preferred name) (319 Da, Ligand)
- Dc1a (Complex from Diguetia canities)
- Voltage-gated sodium channel navpas from american cockroach periplaneta americana (Complex from Periplaneta americana)
- Sodium ion (22 Da, Ligand)
- N-acetyl-d-glucosamine (221 Da, Ligand)
- Sodium channel protein pafpc1 (183 kDa, Protein from Periplaneta americana)
- Mu-diguetoxin-dc1a (6 kDa, Protein from Diguetia canities)
- Water (18 Da, Ligand)
Structure of the human voltage-gated sodium channel Nav1.4 in complex with beta1
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6agf
Q-score: 0.526
Pan X, Li Z, Zhou Q, Shen H, Wu K, Huang X, Chen J, Zhang J, Zhu X, Lei J, Xiong W, Gong H, Xiao B, Yan N
Science (2018) 362 [ Pubmed: 30190309 DOI: doi:10.1126/science.aau2486 ]
- (3beta,14beta,17beta,25r)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en (544 Da, Ligand)
- Sodium channel protein type 4 subunit alpha (212 kDa, Protein from Homo sapiens)
- N-acetyl-d-glucosamine (221 Da, Ligand)
- Complex of human sodium channel protein type 4 subunit alpha and human sodium channel subunit beta-1 (200 kDa, Complex)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
- Human sodium channel protein type 4 subunit alpha (Complex from Homo sapiens)
- Sodium channel subunit beta-1 (24 kDa, Protein from Homo sapiens)
- Beta-d-mannose (180 Da, Ligand)
- Human sodium channel subunit beta-1 (Complex from Homo sapiens)
Cryo-EM structure of a mitochondrial calcium uniporter
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6dt0
Q-score: 0.402
Yoo J, Wu M, Yin Y, Herzik Jr MA, Lander GC, Lee SY
Science (2018) 361 pp. 506-511 [ Pubmed: 29954988 DOI: doi:10.1126/science.aar4056 ]
- Mitochondrial calcium uniporter (Complex from Neurospora crassa)
- Calcium ion (40 Da, Ligand)
- Mitochondrial calcium uniporter (52 kDa, Protein from Neurospora crassa)