Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 8v00
Q-score: 0.552
Zhao J, Chen AQ, Ryu J, Del Marmol J
Science (2024) [ Pubmed: 38870275 DOI: doi:10.1126/science.adn6384 ]
- Apocrypta bakeri orco (Complex from Apocrypta bakeri)
- Odorant receptor or10 (43 kDa, Protein from Aedes aegypti)
- Aaegor10 heterotetramer without ligand (Complex)
- Odorant receptor orco (53 kDa, Protein from Apocrypta bakeri)
- Aedes aegypti or10 (Complex from Aedes aegypti)
AaegOR10 structure bound to o-cresol
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8v02
Q-score: 0.525
Zhao J, Chen AQ, Ryu J, Del Marmol J
Science (2024) [ Pubmed: 38870275 DOI: doi:10.1126/science.adn6384 ]
- O-cresol (108 Da, Ligand)
- Apocrypta bakeri orco (Complex from Apocrypta bakeri)
- Odorant receptor or10 (43 kDa, Protein from Aedes aegypti)
- Aaegor10 heterotetramer bound to o-cresol (Complex)
- Odorant receptor orco (53 kDa, Protein from Apocrypta bakeri)
- Aedes aegypti or10 (Complex from Aedes aegypti)
AgamOR28 structure without ligand
Resolution: 2.62 Å
EM Method: Single-particle
Fitted PDBs: 8v3c
Q-score: 0.569
Zhao J, Chen AQ, Ryu J, Del Marmol J
Science (2024) [ Pubmed: 38870275 DOI: doi:10.1126/science.adn6384 ]
- Agamor28 heterotetramer without ligand (Complex)
- Or28 (45 kDa, Protein from Anopheles gambiae)
- Anopheles gambiae or28 (Complex from Anopheles gambiae)
- Apocrypta bakeri orco (Complex from Apocrypta bakeri)
- Odorant receptor orco (53 kDa, Protein from Apocrypta bakeri)
AgamOR28 structure bound to 2,4,5-trimethylthiazole
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 8v3d
Q-score: 0.571
Zhao J, Chen AQ, Ryu J, Del Marmol J
Science (2024) [ Pubmed: 38870275 DOI: doi:10.1126/science.adn6384 ]
- Agamor28 heterotetramer bound to 2,4,5-trimethylthiazole (Complex)
- Or28 (45 kDa, Protein from Anopheles gambiae)
- Anopheles gambiae or28 (Complex from Anopheles gambiae)
- Apocrypta bakeri orco (Complex from Apocrypta bakeri)
- 2,4,5-trimethyl-1,3-thiazole (127 Da, Ligand)
- Odorant receptor orco (53 kDa, Protein from Apocrypta bakeri)
Cryo-EM structure of human gamma-secretase in complex with Abeta49
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8x52
Q-score: 0.464
Guo X, Li H, Yan C, Lei J, Zhou R, Shi Y
Science (2024) 384 pp. 1091-1095 [ DOI: doi:10.1126/science.adn5820 Pubmed: 38843321 ]
- Nicastrin (78 kDa, Protein from Homo sapiens)
- Gamma-secretase subunit aph-1a (29 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Gamma-secretase subunit pen-2 (12 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Human gamma-secretase in complex with abeta49 (Complex from Homo sapiens)
- Amyloid-beta precursor protein (13 kDa, Protein from Homo sapiens)
- Presenilin-1 (52 kDa, Protein from Homo sapiens)
Cryo-EM structure of human gamma-secretase in complex with Abeta46
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8x53
Q-score: 0.509
Guo X, Li H, Yan C, Lei J, Zhou R, Shi Y
Science (2024) 384 pp. 1091-1095 [ DOI: doi:10.1126/science.adn5820 Pubmed: 38843321 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Gamma-secretase subunit aph-1a (29 kDa, Protein from Homo sapiens)
- Amyloid-beta precursor protein (4 kDa, Protein from Homo sapiens)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Nicastrin (78 kDa, Protein from Homo sapiens)
- Presenilin-1 (52 kDa, Protein from Homo sapiens)
- Human gamma-secretase in complex with abeta46 (Complex from Homo sapiens)
- Gamma-secretase subunit pen-2 (16 kDa, Protein from Homo sapiens)
Cryo-EM structure of human gamma-secretase in complex with APP-C99
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8x54
Q-score: 0.518
Guo X, Li H, Yan C, Lei J, Zhou R, Shi Y
Science (2024) 384 pp. 1091-1095 [ DOI: doi:10.1126/science.adn5820 Pubmed: 38843321 ]
- Nicastrin (78 kDa, Protein from Homo sapiens)
- Gamma-secretase subunit aph-1a (29 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Gamma-secretase subunit pen-2 (12 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Human gamma-secretase in complex with app-c99 (Complex from Homo sapiens)
- Amyloid-beta precursor protein (13 kDa, Protein from Homo sapiens)
- Presenilin-1 (52 kDa, Protein from Homo sapiens)
Structure of the wild-type Arabidopsis ABCB19 in the apo state
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8woi
Q-score: 0.49
Ying W, Wang Y, Wei H, Luo Y, Ma Q, Zhu H, Janssens H, Vukasinovic N, Kvasnica M, Winne JM, Gao Y, Tan S, Friml J, Liu X, Russinova E, Sun L
Science (2024) 383 pp. eadj4591-eadj4591 [ DOI: doi:10.1126/science.adj4591 Pubmed: 38513023 ]
Structure of the wild-type Arabidopsis ABCB19 in the brassinolide-bound state
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8wom
Q-score: 0.451
Ying W, Wang Y, Wei H, Luo Y, Ma Q, Zhu H, Janssens H, Vukasinovic N, Kvasnica M, Winne JM, Gao Y, Tan S, Friml J, Liu X, Russinova E, Sun L
Science (2024) 383 pp. eadj4591-eadj4591 [ DOI: doi:10.1126/science.adj4591 Pubmed: 38513023 ]
Structure of the wild-type Arabidopsis ABCB19 in the brassinolide and AMP-PNP bound state
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8woo
Q-score: 0.401
Ying W, Wang Y, Wei H, Luo Y, Ma Q, Zhu H, Janssens H, Vukasinovic N, Kvasnica M, Winne JM, Gao Y, Tan S, Friml J, Liu X, Russinova E, Sun L
Science (2024) 383 pp. eadj4591-eadj4591 [ DOI: doi:10.1126/science.adj4591 Pubmed: 38513023 ]
- Brassinolide (480 Da, Ligand)
- Abc transporter b family member 19 (136 kDa, Protein from Arabidopsis thaliana)
- Magnesium ion (24 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Purified wild-type abcb19 protein in complex with brassinolide and amp-pnp (Cellular component from Arabidopsis thaliana)