Structure of a human ABCE1-bound 43S pre-initiation complex - State III
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7a09
Q-score: 0.399
Kratzat H, Mackens-Kiani T, Ameismeier M, Potocnjak M, Cheng J, Dacheux E, Namane A, Berninghausen O, Herzog F, Fromont-Racine M, Becker T, Beckmann R
EMBO J (2021) 40 pp. e105179-e105179 [ Pubmed: 33289941 DOI: doi:10.15252/embj.2020105179 ]
- Abce1-bound 43s pre-initiation complex (Complex from Homo sapiens)
- 40s ribosomal protein s24 (15 kDa, Protein from Human)
- Receptor of activated protein c kinase 1 (35 kDa, Protein from Human)
- 18s ribosomal rna (555 kDa, RNA from Human)
- Atp-binding cassette sub-family e member 1 (67 kDa, Protein from Human)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Eukaryotic translation initiation factor 2 subunit 1 (36 kDa, Protein from Human)
- 40s ribosomal protein s12 (14 kDa, Protein from Human)
- 40s ribosomal protein s14 (16 kDa, Protein from Human)
- Eukaryotic translation initiation factor 2 subunit 2 (38 kDa, Protein from Human)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- 40s ribosomal protein s21 (9 kDa, Protein from Human)
- Eukaryotic translation initiation factor 3 subunit l (66 kDa, Protein from Human)
- Ubiquitin-40s ribosomal protein s27a (18 kDa, Protein from Human)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- 40s ribosomal protein s25 (13 kDa, Protein from Human)
- 40s ribosomal protein s23 (15 kDa, Protein from Human)
- 40s ribosomal protein s9 (22 kDa, Protein from Human)
- 40s ribosomal protein s10 (18 kDa, Protein from Human)
- 40s ribosomal protein s29 (6 kDa, Protein from Human)
- Magnesium ion (24 Da, Ligand)
- 40s ribosomal protein s8 (24 kDa, Protein from Human)
- Rna recognition motif (5 kDa, Protein from Human)
- Eukaryotic translation initiation factor 3 subunit i (36 kDa, Protein from Human)
- 40s ribosomal protein s6 (28 kDa, Protein from Human)
- 40s ribosomal protein s3 (26 kDa, Protein from Human)
- 40s ribosomal protein s19 (16 kDa, Protein from Human)
- 40s ribosomal protein s5 (22 kDa, Protein from Human)
- Eukaryotic translation initiation factor 1 (12 kDa, Protein from Human)
- Eukaryotic translation initiation factor 3 subunit a (166 kDa, Protein from Human)
- 40s ribosomal protein s17 (15 kDa, Protein from Human)
- 40s ribosomal protein s27 (9 kDa, Protein from Human)
- Trna (24 kDa, RNA from Human)
- Methionine (149 Da, Ligand)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from Human)
- Eukaryotic translation initiation factor 1a, x-chromosomal (12 kDa, Protein from Human)
- Eukaryotic translation initiation factor 3 subunit m (42 kDa, Protein from Human)
- 40s ribosomal protein s11 (18 kDa, Protein from Human)
- 40s ribosomal protein s18 (17 kDa, Protein from Human)
- Eukaryotic translation initiation factor 3 subunit k (25 kDa, Protein from Human)
- 40s ribosomal protein s26 (13 kDa, Protein from Human)
- Eukaryotic translation initiation factor 3 subunit d (64 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- Eukaryotic translation initiation factor 3 subunit h (39 kDa, Protein from Human)
- 40s ribosomal protein s7 (22 kDa, Protein from Human)
- Eukaryotic translation initiation factor 3 subunit f (37 kDa, Protein from Human)
- 60s ribosomal protein l41 (3 kDa, Protein from Human)
- 40s ribosomal protein s13 (17 kDa, Protein from Human)
- 40s ribosomal protein s28 (7 kDa, Protein from Human)
- 40s ribosomal protein s30 (6 kDa, Protein from Human)
- Eukaryotic translation initiation factor 3 subunit c,eukaryotic translation initiation factor 3 subunit c,eukaryotic translation initiation factor 3 subunit c (106 kDa, Protein from Human)
- 40s ribosomal protein s2 (31 kDa, Protein from Human)
- 40s ribosomal protein s16 (16 kDa, Protein from Human)
- 40s ribosomal protein s3a (30 kDa, Protein from Human)
- Iron/sulfur cluster (351 Da, Ligand)
- 40s ribosomal protein sa (32 kDa, Protein from Human)
- 40s ribosomal protein s15a (14 kDa, Protein from Human)
- 40s ribosomal protein s20 (13 kDa, Protein from Human)
- 40s ribosomal protein s15 (17 kDa, Protein from Human)
- Eukaryotic translation initiation factor 2 subunit 3 (51 kDa, Protein from Human)
- Eukaryotic translation initiation factor 3 subunit b (92 kDa, Protein from Human)
- Eukaryotic translation initiation factor 3 subunit e (52 kDa, Protein from Human)