Structure of mouse RyR1 in complex with S100A1 (high-Ca2+/CFF/ATP dataset)
Resolution: 3.56 Å
EM Method: Single-particle
Fitted PDBs: 8vk4
Q-score: 0.44
To Be Published
- Protein s100a1 (10 kDa, Protein from Mus musculus)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Caffeine (194 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Mus musculus)
- Complex of ryr1 with calstabin-1 and s100a1 (high-ca2+/cff/atp condition) (Complex from Mus musculus)
- Ryanodine receptor 1 (565 kDa, Protein from Mus musculus)
Structure of mouse RyR1 in complex with S100A1 (EGTA-only dataset)
Resolution: 3.21 Å
EM Method: Single-particle
Fitted PDBs: 8vk3
Q-score: 0.491
To Be Published
- Ryanodine receptor 1 (565 kDa, Protein from Mus musculus)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Mus musculus)
- Protein s100a1 (10 kDa, Protein from Mus musculus)
- Complex of ryr1 with calstabin-1 and s100a1 (egta condition) (Complex from Mus musculus)
- Zinc ion (65 Da, Ligand)
Structure of mouse RyR1 (EGTA-only dataset)
Resolution: 2.53 Å
EM Method: Single-particle
Fitted PDBs: 8vjj
Q-score: 0.597
To Be Published
- Complex of ryr1 with calstabin-1 (egta condition) (Complex from Mus musculus)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Mus musculus)
- Zinc ion (65 Da, Ligand)
- Ryanodine receptor 1 (565 kDa, Protein from Mus musculus)
Structure of mouse RyR1 (high-Ca2+/CFF/ATP dataset)
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 8vjk
Q-score: 0.533
To Be Published
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Caffeine (194 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Complex of ryr1 with calstabin-1 (high-ca2+/cff/atp condition) (Complex from Mus musculus)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Mus musculus)
- Zinc ion (65 Da, Ligand)
- Ryanodine receptor 1 (565 kDa, Protein from Mus musculus)
Structure of PKA phosphorylated human RyR2-R420Q in the closed state in the presence of ARM210
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8uxe
Q-score: 0.391
To Be Published
- Complex of ryr2-r420q and calstabin-2 in the presence of arm210 (Complex)
- Peptidyl- cis-trans isomerase fkbp1b (Complex from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryanodine receptor 2 (565 kDa, Protein from Homo sapiens)
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Ryanodine receptor 2 (Complex from Homo sapiens)
- 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5h)-yl)methyl]benzoic acid (329 Da, Ligand)
- Zinc ion (65 Da, Ligand)
Structure of PKA phosphorylated human RyR2-R420W in the primed state
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8uxf
Q-score: 0.454
To Be Published
- Peptidyl- cis-trans isomerase fkbp1b (Complex from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Ryanodine receptor 2 (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Complex of ryr2-r420w and calstabin-2 (Complex)
- Ryanodine receptor 2 (565 kDa, Protein from Homo sapiens)
Structure of PKA phosphorylated human RyR2-R420W in the closed state in the presence of ARM210
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 8uxg
Q-score: 0.434
To Be Published
- Peptidyl- cis-trans isomerase fkbp1b (Complex from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Ryanodine receptor 2 (Complex from Homo sapiens)
- 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5h)-yl)methyl]benzoic acid (329 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Complex of ryr2-r420w and calstabin-2 (Complex)
- Ryanodine receptor 2 (565 kDa, Protein from Homo sapiens)
Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium
Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 8uxh
Q-score: 0.366
To Be Published
- Ryanodine receptor 2 (565 kDa, Protein from Homo sapiens)
- Peptidyl- cis-trans isomerase fkbp1b (Complex from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryanodine receptor 2 (Complex from Homo sapiens)
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Complex of ryr2-r420w and calstabin-2 (Complex)
Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 8uxi
Q-score: 0.39
To Be Published
- Ryanodine receptor 2 (565 kDa, Protein from Homo sapiens)
- Peptidyl- cis-trans isomerase fkbp1b (Complex from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryanodine receptor 2 (Complex from Homo sapiens)
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Complex of ryr2-r420w and calstabin-2 (Complex)
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 8uxl
Q-score: 0.417
To Be Published
- Ryanodine receptor 2 (565 kDa, Protein from Homo sapiens)
- Complex of ryr2-r420w, calstabin-2, and calmodulin (Complex)
- Peptidyl- cis-trans isomerase fkbp1b (Complex from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryanodine receptor 2 (Complex from Homo sapiens)
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
- Calmodulin (Complex from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Zinc ion (65 Da, Ligand)