Yeast CTP Synthase (URA8) tetramer bound to ATP/UTP at neutral pH
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7rkh
Q-score: 0.535
Hansen JM, Horowitz A, Lynch EM, Farrell DP, Quispe J, DiMaio F, Kollman JM
eLife (2021) 10 [ Pubmed: 34734801 DOI: doi:10.7554/eLife.73368 ]
- Uridine 5'-triphosphate (484 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Ctp synthase (62 kDa, Protein from Saccharomyces cerevisiae)
- Yeast ctp synthase (ura8) tetramer bound to atp/utp at neutral ph (256 MDa, Complex from Saccharomyces cerevisiae)
Yeast CTP Synthase (URA8) Filament bound to ATP/UTP at low pH
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7rl0
Q-score: 0.312
Hansen JM, Horowitz A, Lynch EM, Farrell DP, Quispe J, DiMaio F, Kollman JM
eLife (2021) 10 [ DOI: doi:10.7554/eLife.73368 Pubmed: 34734801 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Yeast ctp synthase (ura8) filament bound to atp/utp at low ph (256 MDa, Complex from Saccharomyces cerevisiae)
- Ctp synthase (62 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Uridine 5'-triphosphate (484 Da, Ligand)
Yeast CTP Synthase (URA8) Filament bound to CTP at low pH
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7rl5
Q-score: 0.247
Hansen JM, Horowitz A, Lynch EM, Farrell DP, Quispe J, DiMaio F, Kollman JM
eLife (2021) 10 [ Pubmed: 34734801 DOI: doi:10.7554/eLife.73368 ]
- Ctp synthase (62 kDa, Protein from Saccharomyces cerevisiae)
- Yeast ctp synthase filament with ctp bound (256 MDa, Complex from Saccharomyces cerevisiae)
- Cytidine-5'-triphosphate (483 Da, Ligand)
Yeast CTP Synthase (Ura7) filament bound to CTP at low pH
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7rmc
Q-score: 0.18
Hansen JM, Horowitz A, Lynch EM, Farrell DP, Quispe J, DiMaio F, Kollman JM
eLife (2021) 10 [ Pubmed: 34734801 DOI: doi:10.7554/eLife.73368 ]
- Ctp synthase 1 with bound ctp (256 MDa, Complex from Saccharomyces cerevisiae)
- Ctp synthase 1 (62 kDa, Protein from Saccharomyces cerevisiae)
- Cytidine-5'-triphosphate (483 Da, Ligand)
Substrate-bound Ura7 filament at low pH
Resolution: 7.3 Å
EM Method: Single-particle
Fitted PDBs: 7rmf
Q-score: 0.099
Hansen JM, Horowitz A, Lynch EM, Farrell DP, Quispe J, DiMaio F, Kollman JM
eLife (2021) 10 [ Pubmed: 34734801 DOI: doi:10.7554/eLife.73368 ]
Yeast CTP Synthase (Ura7) Bundle bound to substrates at low pH
Resolution: 6.6 Å
EM Method: Single-particle
Fitted PDBs: 7rmk
Q-score: 0.117
Hansen JM, Horowitz A, Lynch EM, Farrell DP, Quispe J, DiMaio F, Kollman JM
eLife (2021) 10 [ DOI: doi:10.7554/eLife.73368 Pubmed: 34734801 ]
- Uridine 5'-triphosphate (484 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ctp synthase (61 kDa, Protein from Saccharomyces cerevisiae)
- Ctp synthase bundle assembled with substrates (Complex from Saccharomyces cerevisiae)
Yeast CTP Synthase (Ura7) Bundle bound to Products at low pH
Resolution: 7.0 Å
EM Method: Single-particle
Fitted PDBs: 7rmo
Q-score: 0.121
Hansen JM, Horowitz A, Lynch EM, Farrell DP, Quispe J, DiMaio F, Kollman JM
eLife (2021) 10 [ Pubmed: 34734801 DOI: doi:10.7554/eLife.73368 ]
- Cytidine-5'-triphosphate (483 Da, Ligand)
- Ctp synthase (62 kDa, Protein from Saccharomyces cerevisiae)
- Ctp synthase bundle assembled with products (Complex from Saccharomyces cerevisiae)
Yeast CTP Synthase (Ura7) H360R Filament bound to Substrates
Resolution: 6.7 Å
EM Method: Single-particle
Fitted PDBs: 7rmv
Q-score: 0.135
Hansen JM, Horowitz A, Lynch EM, Farrell DP, Quispe J, DiMaio F, Kollman JM
eLife (2021) 10 [ DOI: doi:10.7554/eLife.73368 Pubmed: 34734801 ]
- Ctp synthase (61 kDa, Protein from Saccharomyces cerevisiae)
- Uridine 5'-triphosphate (484 Da, Ligand)
- Ctp synthase bundle assembled with substrates (Complex from Saccharomyces cerevisiae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
Yeast CTP Synthase (Ura7) H360R Filament bound to Substrates
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7rnl
Q-score: 0.356
Hansen JM, Horowitz A, Lynch EM, Farrell DP, Quispe J, DiMaio F, Kollman JM
eLife (2021) 10 [ Pubmed: 34734801 DOI: doi:10.7554/eLife.73368 ]
- Ctp synthase bundle assembled with substrates (Complex from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Ctp synthase (62 kDa, Protein from Saccharomyces cerevisiae)
- Cytidine-5'-triphosphate (483 Da, Ligand)
Yeast CTP Synthase (Ura8) Bundle Bound to Substrates at Low pH
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7rnr
Q-score: 0.187
Hansen JM, Horowitz A, Lynch EM, Farrell DP, Quispe J, DiMaio F, Kollman JM
eLife (2021) 10 [ Pubmed: 34734801 DOI: doi:10.7554/eLife.73368 ]
- Uridine 5'-triphosphate (484 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Ctp synthase bundle assembled with substrates (Complex from Saccharomyces cerevisiae)
- Ctp synthase (62 kDa, Protein from Saccharomyces cerevisiae)