Pyochelin synthetase, a dimeric nonribosomal peptide synthetase elongation module
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 7emy
Q-score: 0.43
Wang J, Li D, Chen L, Cao W, Kong L, Zhang W, Croll T, Deng Z, Liang J, Wang Z
Nat Commun (2022) 13 pp. 592-592 [ Pubmed: 35105906 DOI: doi:10.1038/s41467-022-28284-x ]
- Pyochelin synthetase, a dimeric nonribosomal peptide synthetase elongation module (160 MDa, Cellular component from Pseudomonas aeruginosa PAO1)
- Adenosine monophosphate (347 Da, Ligand)
- Dihydroaeruginoic acid synthetase (158 kDa, Protein from Pseudomonas aeruginosa PAO1)
- 4'-phosphopantetheine (358 Da, Ligand)
- Cysteine (121 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- 2-hydroxybenzoic acid (138 Da, Ligand)
Pyochelin synthetase, a dimeric nonribosomal peptide synthetase elongation module-after-condensation
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 7en1
Q-score: 0.386
Wang J, Li D, Chen L, Cao W, Kong L, Zhang W, Croll T, Deng Z, Liang J, Wang Z
Nat Commun (2022) 13 pp. 592-592 [ Pubmed: 35105906 DOI: doi:10.1038/s41467-022-28284-x ]
- Pyochelin synthetase, a dimeric nonribosomal peptide synthetase elongation module (160 MDa, Cellular component from Pseudomonas aeruginosa PAO1)
- (4s)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid (223 Da, Ligand)
- Adenosine monophosphate (347 Da, Ligand)
- Dihydroaeruginoic acid synthetase (158 kDa, Protein from Pseudomonas aeruginosa PAO1)
- 4'-phosphopantetheine (358 Da, Ligand)
- Cysteine (121 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- 2-hydroxybenzoic acid (138 Da, Ligand)
Resolution: 3.78 Å
EM Method: Single-particle
Fitted PDBs: 7en2
Q-score: 0.33
Wang J, Li D, Chen L, Cao W, Kong L, Zhang W, Croll T, Deng Z, Liang J, Wang Z
Nat Commun (2022) 13 pp. 592-592 [ Pubmed: 35105906 DOI: doi:10.1038/s41467-022-28284-x ]
- Dihydroaeruginoic acid synthetase (158 kDa, Protein from Pseudomonas aeruginosa PAO1)
- Pyochelin synthetase, a dimeric nonribosomal peptide synthetase elongation module (160 MDa, Cellular component from Pseudomonas aeruginosa PAO1)
- Adenosine monophosphate (347 Da, Ligand)
- 4'-phosphopantetheine (358 Da, Ligand)
Structure of the P. aeruginosa ExoY-F-actin complex
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7p1g
Q-score: 0.46
Belyy A, Merino F, Mechold U, Raunser S
Nat Commun (2021) 12 pp. 6628-6628 [ Pubmed: 34785651 DOI: doi:10.1038/s41467-021-26889-2 ]
- 3'-deoxy-guanosine-5'-triphosphate (507 Da, Ligand)
- Phalloidin (808 Da, Protein from Amanita phalloides)
- Actin, alpha skeletal muscle (42 kDa, Protein from Rabbit)
- The complex of p. aeruginosa exoy with f-actin (Complex)
- Phosphate ion (94 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Maltose/maltodextrin-binding periplasmic protein,adenylate cyclase exoy (84 kDa, Protein from Pseudomonas aeruginosa PAO1)
Cryo-EM structure of P.aeruginosa MlaFEBD with ADP-V
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7ch8
Q-score: 0.401
Zhou C, Shi H, Zhang M, Zhou L, Xiao L, Feng S, Im W, Zhou M, Zhang X, Huang Y
J Mol Biol (2021) 433 pp. 166986-166986 [ DOI: doi:10.1016/j.jmb.2021.166986 Pubmed: 33845086 ]
- E.coli mlafeb bond with amppnp (Complex from Escherichia coli K-12)
- Mlad domain-containing protein (16 kDa, Protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1))
- Probable permease of abc transporter (28 kDa, Protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1))
- Probable atp-binding component of abc transporter (29 kDa, Protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1))
- Adp metavanadate (527 Da, Ligand)
- 2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate (648 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Stas domain-containing protein (10 kDa, Protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1))
Cryo-EM structure of P.aeruginosa MlaFEBD
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7ch9
Q-score: 0.427
Zhou C, Shi H, Zhang M, Zhou L, Xiao L, Feng S, Im W, Zhou M, Zhang X, Huang Y
J Mol Biol (2021) 433 pp. 166986-166986 [ DOI: doi:10.1016/j.jmb.2021.166986 Pubmed: 33845086 ]
- Mlad domain-containing protein (16 kDa, Protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1))
- Probable permease of abc transporter (28 kDa, Protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1))
- Cryo-em structure of p.aeruginosa mlafebd (Complex from Pseudomonas aeruginosa PAO1)
- Probable atp-binding component of abc transporter (29 kDa, Protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1))
- 2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate (648 Da, Ligand)
- Stas domain-containing protein (10 kDa, Protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1))
Cryo-EM structure of P.aeruginosa MlaFEBD with AMPPNP
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7cha
Q-score: 0.386
Zhou C, Shi H, Zhang M, Zhou L, Xiao L, Feng S, Im W, Zhou M, Zhang X, Huang Y
J Mol Biol (2021) 433 pp. 166986-166986 [ DOI: doi:10.1016/j.jmb.2021.166986 Pubmed: 33845086 ]
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Mlad domain-containing protein (16 kDa, Protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1))
- Probable atp-binding component of abc transporter,p.aeruginosa mla f (29 kDa, Protein from Pseudomonas aeruginosa PAO1)
- Cryo-em structure of p.aeruginosa mlafebd with amppnp (Complex from Pseudomonas aeruginosa PAO1)
- Probable permease of abc transporter (28 kDa, Protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1))
- 2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate (648 Da, Ligand)
- Stas domain-containing protein (10 kDa, Protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1))