The structure of MutS bound to two molecules of AMPPNP
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7oto
Q-score: 0.499
Borsellini A, Kunetsky V, Friedhoff P, Lamers MH
Nat Struct Mol Biol (2022) 29 pp. 59-66 [ Pubmed: 35013597 DOI: doi:10.1038/s41594-021-00707-1 ]
- Dna mismatch repair protein muts (190 kDa, Cellular component from Escherichia coli)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Dna mismatch repair protein muts (90 kDa, Protein from Escherichia coli (strain K12))
- Magnesium ion (24 Da, Ligand)
The structure of MutS bound to two molecules of ADP-Vanadate
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7ou0
Q-score: 0.413
Borsellini A, Kunetsky V, Friedhoff P, Lamers MH
Nat Struct Mol Biol (2022) 29 pp. 59-66 [ Pubmed: 35013597 DOI: doi:10.1038/s41594-021-00707-1 ]
- Magnesium ion (24 Da, Ligand)
- Dna mismatch repair protein muts (90 kDa, Protein from Escherichia coli (strain K12))
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dna mismatch repair protein muts (190 kDa, Cellular component from Escherichia coli)
- Vanadate ion (114 Da, Ligand)
The structure of MutS bound to two molecules of ADP
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 7ou2
Q-score: 0.18
Borsellini A, Kunetsky V, Friedhoff P, Lamers MH
Nat Struct Mol Biol (2022) 29 pp. 59-66 [ Pubmed: 35013597 DOI: doi:10.1038/s41594-021-00707-1 ]
- Dna mismatch repair protein muts (190 kDa, Cellular component from Escherichia coli)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dna mismatch repair protein muts (96 kDa, Protein from Escherichia coli)
The structure of MutS bound to one molecule of ATP and one molecule of ADP
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7ou4
Q-score: 0.446
Borsellini A, Kunetsky V, Friedhoff P, Lamers MH
Nat Struct Mol Biol (2022) 29 pp. 59-66 [ Pubmed: 35013597 DOI: doi:10.1038/s41594-021-00707-1 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dna mismatch repair protein muts (90 kDa, Protein from Escherichia coli)
- Dna mismatch repair protein muts (190 kDa, Cellular component from Escherichia coli)
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7ai5
Q-score: 0.239
Fernandez-Leiro R, Bhairosing-Kok D, Kunetsky V, Laffeber C, Winterwerp HH, Groothuizen F, Fish A, Lebbink JHG, Friedhoff P, Sixma TK, Lamers MH
Nat Struct Mol Biol (2021) 28 pp. 373-381 [ Pubmed: 33820992 DOI: doi:10.1038/s41594-021-00577-7 ]
- Dna mismatch repair protein muts (Complex from Escherichia coli)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Dna (Complex from synthetic construct)
- Dna mismatch repair protein muts (95 kDa, Protein from Escherichia coli)
- Dna (5'-d(p*cp*gp*gp*tp*ap*cp*cp*cp*ap*ap*tp*tp*cp*gp*cp*cp*cp*tp*ap*tp*ap*g)-3') (6 kDa, DNA from synthetic construct)
- Dna (5'-d(p*cp*tp*ap*tp*ap*gp*gp*gp*cp*gp*ap*ap*tp*tp*gp*gp*gp*tp*ap*cp*cp*g)-3') (6 kDa, DNA from synthetic construct)
- Muts loaded on matched dna in the presence of atp (190 kDa, Complex)