Structure of the bacterial type VI secretion system effector RhsA.
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7q97
Q-score: 0.518
Gunther P, Quentin D, Ahmad S, Sachar K, Gatsogiannis C, Whitney JC, Raunser S
PLoS Pathog (2022) 18 pp. e1010182-e1010182 [ DOI: doi:10.1371/journal.ppat.1010182 Pubmed: 34986192 ]
- Structure of rhsa. (164 kDa, Cellular component from Pseudomonas protegens Pf-5)
- Rhs family protein (159 kDa, Protein from Pseudomonas protegens Pf-5)
Structure of VgrG1 from Pseudomonas protegens.
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7q5p
Q-score: 0.46
Gunther P, Quentin D, Ahmad S, Sachar K, Gatsogiannis C, Whitney JC, Raunser S
PLoS Pathog (2022) 18 pp. e1010182-e1010182 [ DOI: doi:10.1371/journal.ppat.1010182 Pubmed: 34986192 ]
Cryo-EM structure of MDA5-dsRNA in complex with TRIM65 PSpry domain (Monomer)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7jl0
Q-score: 0.395
Kato K, Ahmad S, Zhu Z, Young JM, Mu X, Park S, Malik HS, Hur S
Mol Cell (2021) 81 pp. 599-613.e8 [ DOI: doi:10.1016/j.molcel.2020.11.047 Pubmed: 33373584 ]
- Interferon-induced helicase c domain-containing protein 1 (84 kDa, Protein from Homo sapiens)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Tripartite motif-containing protein 65 (21 kDa, Protein from Homo sapiens)
- Rna (5'-r(p*up*cp*ap*gp*up*cp*ap*gp*up*cp*ap*gp*up*c)-3') (4 kDa, RNA from Homo sapiens)
- Ternary complex of mda5:dsrna:trim65 (Complex from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Rna (5'-r(p*gp*ap*cp*up*gp*ap*cp*up*gp*ap*cp*up*gp*a)-3') (4 kDa, RNA from Homo sapiens)
Cryo-EM structure of RIG-I:dsRNA in complex with RIPLET PrySpry domain (monomer)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7jl1
Q-score: 0.489
Kato K, Ahmad S, Zhu Z, Young JM, Mu X, Park S, Malik HS, Hur S
Mol Cell (2021) 81 pp. 599-613.e8 [ DOI: doi:10.1016/j.molcel.2020.11.047 Pubmed: 33373584 ]
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Ternary complex of rig-i:dsrna:riplet pryspry (Complex from Homo sapiens)
- Dsrna strand 2 (4 kDa, RNA from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- E3 ubiquitin-protein ligase rnf135 (21 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Dsrna strand 1 (4 kDa, RNA from Homo sapiens)
- Antiviral innate immune response receptor rig-i (82 kDa, Protein from Homo sapiens)
Cryo-EM structure of MDA5-dsRNA filament in complex with TRIM65 PSpry domain (Trimer)
Resolution: 4.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 7jl2
Q-score: 0.362
Kato K, Ahmad S, Zhu Z, Young JM, Mu X, Park S, Malik HS, Hur S
Mol Cell (2021) 81 pp. 599-613.e8 [ DOI: doi:10.1016/j.molcel.2020.11.047 Pubmed: 33373584 ]
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Rna (44-mer) (13 kDa, RNA from Homo sapiens)
- Tripartite motif-containing protein 65 (21 kDa, Protein from Homo sapiens)
- Rna (44-mer) (14 kDa, RNA from Homo sapiens)
- Interferon-induced helicase c domain-containing protein 1 (84 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Ternary complex of mda5-dsrna-trim65 (Complex from Homo sapiens)
Cryo-EM structure of RIG-I:dsRNA filament in complex with RIPLET PrySpry domain (trimer)
Resolution: 4.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 7jl3
Q-score: 0.296
Kato K, Ahmad S, Zhu Z, Young JM, Mu X, Park S, Malik HS, Hur S
Mol Cell (2021) 81 pp. 599-613.e8 [ DOI: doi:10.1016/j.molcel.2020.11.047 Pubmed: 33373584 ]
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Dsrna strand 2 (13 kDa, RNA from Homo sapiens)
- Dsrna strand1 (13 kDa, RNA from Homo sapiens)
- Antiviral innate immune response receptor rig-i (82 kDa, Protein from Homo sapiens)
- Ternary complex of dsrna-bound rig-i filament with riplet pryspry domain (Complex from Homo sapiens)
- E3 ubiquitin-protein ligase rnf135 (21 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Zinc ion (65 Da, Ligand)
Setiaputra D, Ahmad S, Dalwadi U, Steunou AL, Lu S, Ross JD, Dong MQ, Cote J, Yip CK
Mol Cell Biol (2018) 38 [ Pubmed: 29463645 DOI: doi:10.1128/MCB.00570-17 ]
- Chromatin-modifying complex (1 MDa, Complex from Saccharomyces cerevisiae)
Electron cryo-microscopy of the Type VI secretion "pre-firing" VgrG1-Tse6-EagT6-EF-Tu-Tsi6 complex
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6h3l
Q-score: 0.225
Quentin D, Ahmad S, Shanthamoorthy P, Mougous JD, Whitney JC, Raunser S
Nat Microbiol (2018) 3 pp. 1142-1152 [ Pubmed: 30177742 DOI: doi:10.1038/s41564-018-0238-z ]
- Type vi secretion "pre-firing" vgrg1-tse6-eagt6-ef-tu-tsi6 complex (43 kDa, Complex)
- Effector associated gene with tse6 (Complex from Pseudomonas aeruginosa PAO1)
- Vgrg1 (72 kDa, Protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1))
- Type vi secretion immunity 6 (Complex from Pseudomonas aeruginosa PAO1)
- Elongation factor tu 1 (Complex from Escherichia coli BL21)
- Type vi secretion exported 6 (Complex from Pseudomonas aeruginosa PAO1)
- Valine-glycine repeat protein 1 (Complex from Pseudomonas aeruginosa PAO1)
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 6h3n
Q-score: 0.475
Quentin D, Ahmad S, Shanthamoorthy P, Mougous JD, Whitney JC, Raunser S
Nat Microbiol (2018) 3 pp. 1142-1152 [ Pubmed: 30177742 DOI: doi:10.1038/s41564-018-0238-z ]
