Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 6i52
Q-score: 0.101
Yates LA, Aramayo RJ, Pokhrel N, Caldwell CC, Kaplan JA, Perera RL, Spies M, Antony E, Zhang X
Nat Commun (2018) 9 pp. 5447-5447 [ DOI: doi:10.1038/s41467-018-07883-7 Pubmed: 30575763 ]
- Replication factor a protein 2 (14 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Replication factor a protein 1 (20 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Replication factor a protein 3 (13 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Replication protein a heterotrimeric complex with ssdna (120 kDa, Complex)
- Dna (5'-d(p*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*t)-3') (6 kDa, DNA from synthetic construct)
- Replication protein a heterotrimeric complex with ssdna (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Replication protein a heterotrimeric complex with ssdna (Complex from synthetic construct)
Cryo-EM structure of the human INO80 complex bound to nucleosome
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 6hts
Q-score: 0.181
Ayala R, Willhoft O, Aramayo RJ, Wilkinson M, McCormack EA, Ocloo L, Wigley DB, Zhang X
Nature (2018) 556 pp. 391-395 [ DOI: doi:10.1038/s41586-018-0021-6 Pubmed: 29643506 ]
- Ino80 complex subunit b (38 kDa, Protein from synthetic construct)
- Actin-related protein 5 (68 kDa, Protein from Homo sapiens)
- Nucleosome (Complex from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Ruvb-like 1 (50 kDa, Protein from Homo sapiens)
- Human ino80 (Complex from synthetic construct)
- Dna (142-mer) (62 kDa, DNA from synthetic construct)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Dna (142-mer) (61 kDa, DNA from synthetic construct)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Histone subunits (Complex from Homo sapiens)
- Histone h2a type 1-b/e (14 kDa, Protein from Homo sapiens)
- Histone h2b type 1-j (13 kDa, Protein from Homo sapiens)
- Ruvb-like 2 (51 kDa, Protein from Homo sapiens)
- Complex of core human ino80 with nucleosome (Complex from Homo sapiens)
- Dna helicase ino80 (146 kDa, Protein from Homo sapiens)
Aramayo RJ, Willhoft O, Ayala R, Bythell-Douglas R, Wigley DB, Zhang X
Nat Struct Mol Biol (2018) 25 pp. 37-44 [ DOI: doi:10.1038/s41594-017-0003-7 Pubmed: 29323271 ]
- Human ino80 core complex (800 kDa, Complex from Homo sapiens)
High resolution INO80 core complex
Resolution: 4.06 Å
EM Method: Single-particle
Fitted PDBs: 5oaf
Q-score: 0.315
Aramayo RJ, Willhoft O, Ayala R, Bythell-Douglas R, Wigley DB, Zhang X
Nat Struct Mol Biol (2018) 25 pp. 37-44 [ Pubmed: 29323271 DOI: doi:10.1038/s41594-017-0003-7 ]
- Ruvb-like 1 (50 kDa, Protein from Homo sapiens)
- Human ino80 core complex (800 kDa, Complex from Homo sapiens)
- Ruvb-like 2 (51 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Cryo-EM structure of a human INO80 sub-complex (RuvBL1/2, Ino80)
Aramayo RJ, Willhoft O, Ayala R, Bythell-Douglas R, Wigley DB, Zhang X
Nat Struct Mol Biol (2018) 25 pp. 37-44 [ Pubmed: 29323271 DOI: doi:10.1038/s41594-017-0003-7 ]
Cryo-EM structure of a human INO80 sub-complex (RuvBL1/2, Ino80, Arp5, Ies6, Ies2)
Aramayo RJ, Willhoft O, Ayala R, Bythell-Douglas R, Wigley DB, Zhang X
Nat Struct Mol Biol (2018) 25 pp. 37-44 [ Pubmed: 29323271 DOI: doi:10.1038/s41594-017-0003-7 ]