CryoEM structure of human S-OPA1 assembled on lipid membrane in membrane-adjacent state
Resolution: 4.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ct1
Q-score: 0.144
von der Malsburg A, Sapp GM, Zuccaro KE, von Appen A, Moss 3rd FR, Kalia R, Bennett JA, Abriata LA, Dal Peraro M, van der Laan M, Frost A, Aydin H
Nature (2023) 620 pp. 1101-1108 [ DOI: doi:10.1038/s41586-023-06441-6 Pubmed: 37612504 ]
- Opa1 (820 kDa, Complex from Homo sapiens)
- Dynamin-like 120 kda protein, mitochondrial (111 kDa, Protein from Homo sapiens)
CryoEM structure of human S-OPA1 assembled on lipid membrane in membrane-distal state
Resolution: 6.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ct9
Q-score: 0.133
von der Malsburg A, Sapp GM, Zuccaro KE, von Appen A, Moss 3rd FR, Kalia R, Bennett JA, Abriata LA, Dal Peraro M, van der Laan M, Frost A, Aydin H
Nature (2023) 620 pp. 1101-1108 [ DOI: doi:10.1038/s41586-023-06441-6 Pubmed: 37612504 ]
- Cardiolipin (1 kDa, Ligand)
- Opa1 (820 kDa, Complex from Homo sapiens)
- Dynamin-like 120 kda protein, mitochondrial (111 kDa, Protein from Homo sapiens)
CryoEM structure of human LACTB filament
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 7ulw
Q-score: 0.486
Bennett JA, Steward LR, Rudolph J, Voss AP, Aydin H
PLoS Biol (2022) 20 pp. e3001899-e3001899 [ Pubmed: 36534696 DOI: doi:10.1371/journal.pbio.3001899 ]
- Lactb (510 kDa, Complex from Homo sapiens)
- Serine beta-lactamase-like protein lactb, mitochondrial (51 kDa, Protein from Homo sapiens)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7ssp
Q-score: 0.481
Manicki M, Aydin H, Abriata LA, Overmyer KA, Guerra RM, Coon JJ, Dal Peraro M, Frost A, Pagliarini DJ
Mol Cell (2022) 82 pp. 4307-4323.e10 [ Pubmed: 36306796 DOI: doi:10.1016/j.molcel.2022.10.003 ]
- Ubiquinone biosynthesis protein coq9, mitochondrial (35 kDa, Protein from Homo sapiens)
- 5-demethoxyubiquinone hydroxylase, mitochondrial (24 kDa, Protein from Homo sapiens)
- Human coq7:coq9 complex (Complex from Homo sapiens)
Structure of the NADH-bound human COQ7:COQ9 complex by single-particle electron cryo-microscopy
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 7sss
Q-score: 0.599
Manicki M, Aydin H, Abriata LA, Overmyer KA, Guerra RM, Coon JJ, Dal Peraro M, Frost A, Pagliarini DJ
Mol Cell (2022) 82 pp. 4307-4323.e10 [ Pubmed: 36306796 DOI: doi:10.1016/j.molcel.2022.10.003 ]
- Ubiquinone biosynthesis protein coq9, mitochondrial (35 kDa, Protein from Homo sapiens)
- Nicotinamide-adenine-dinucleotide (663 Da, Ligand)
- 5-demethoxyubiquinone hydroxylase, mitochondrial (24 kDa, Protein from Homo sapiens)
- Human coq7:coq9 complex (Complex from Homo sapiens)
- Water (18 Da, Ligand)
- (1s)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate (720 Da, Ligand)
- 2-[(2e,6e,10e,14e,18e,22e,26e)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaenyl]phenol (639 Da, Ligand)