Resolution: 3.94 Å
EM Method: Single-particle
Fitted PDBs: 8kci
Q-score: 0.356
Huang Y, Xue C, Bu R, Wu C, Li J, Zhang J, Chen J, Shi Z, Chen Y, Wang Y, Liu Z
Nat Commun (2024) 15 pp. 4811-4811 [ Pubmed: 38844452 DOI: doi:10.1038/s41467-024-49204-1 ]
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Atp-bound hmrp5 outward-open (Complex from Homo sapiens)
- Atp-binding cassette sub-family c member 5 (160 kDa, Protein from Homo sapiens)
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8wi0
Q-score: 0.482
Huang Y, Xue C, Bu R, Wu C, Li J, Zhang J, Chen J, Shi Z, Chen Y, Wang Y, Liu Z
Nat Commun (2024) 15 pp. 4811-4811 [ Pubmed: 38844452 DOI: doi:10.1038/s41467-024-49204-1 ]
- Wt-hmrp5 (Complex from Homo sapiens)
- Atp-binding cassette sub-family c member 5 (160 kDa, Protein from Homo sapiens)
- Atp-binding cassette sub-family c member 5 (2 kDa, Protein from Homo sapiens)
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 8wi3
Q-score: 0.431
Huang Y, Xue C, Bu R, Wu C, Li J, Zhang J, Chen J, Shi Z, Chen Y, Wang Y, Liu Z
Nat Commun (2024) 15 pp. 4811-4811 [ Pubmed: 38844452 DOI: doi:10.1038/s41467-024-49204-1 ]
- Hmrp5-nd inward-open (Complex from Homo sapiens)
- Atp-binding cassette sub-family c member 5 (164 kDa, Protein from Homo sapiens)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8wi4
Q-score: 0.431
Huang Y, Xue C, Bu R, Wu C, Li J, Zhang J, Chen J, Shi Z, Chen Y, Wang Y, Liu Z
Nat Commun (2024) 15 pp. 4811-4811 [ Pubmed: 38844452 DOI: doi:10.1038/s41467-024-49204-1 ]
- Hmrp5-m6 inward open (Complex from Homo sapiens)
- Atp-binding cassette sub-family c member 5 (160 kDa, Protein from Homo sapiens)
Cryo-EM structure of ATP13A2 in the E1-ATP state
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8iek
Q-score: 0.377
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Magnesium ion (24 Da, Ligand)
- Cryo-em structure of atp13a2 in the e1-atp state (Complex from Homo sapiens)
- Polyamine-transporting atpase 13a2 (128 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
Cryo-EM structure of ATP13A2 in the E1-like state
Resolution: 5.65 Å
EM Method: Single-particle
Fitted PDBs: 8iel
Q-score: 0.229
Cryo-EM structure of ATP13A2 in the E2P state
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8iem
Q-score: 0.262
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ DOI: doi:10.1038/s41467-023-37741-0 Pubmed: 37031211 ]
- Spermine (202 Da, Ligand)
- Beryllium trifluoride ion (66 Da, Ligand)
- Polyamine-transporting atpase 13a2 (123 kDa, Protein from Homo sapiens)
- Polyamine-transporting atpase 13a2 (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
Cryo-EM structure of ATP13A2 in the E2-Pi state
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8ien
Q-score: -0.047
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ Pubmed: 37031211 DOI: doi:10.1038/s41467-023-37741-0 ]
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Polyamine-transporting atpase 13a2 (128 kDa, Protein from Homo sapiens)
- Cryo-em structure of atp13a2 in the e2-pi state (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Spermine (202 Da, Ligand)
Cryo-EM structure of ATP13A2 in the nominal E1P state
Resolution: 3.78 Å
EM Method: Single-particle
Fitted PDBs: 8ieo
Q-score: 0.312
Mu J, Xue C, Fu L, Yu Z, Nie M, Wu M, Chen X, Liu K, Bu R, Huang Y, Yang B, Han J, Jiang Q, Chan KC, Zhou R, Li H, Huang A, Wang Y, Liu Z
Nat Commun (2023) 14 pp. 1978-1978 [ Pubmed: 37031211 DOI: doi:10.1038/s41467-023-37741-0 ]
- Cryo-em structure of atp13a2 in the nominal e1p state (Complex from Homo sapiens)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Polyamine-transporting atpase 13a2 (128 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Spermine (202 Da, Ligand)