Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 3, Vo
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9b8o
Q-score: 0.513
Coupland CE, Karimi R, Bueler SA, Liang Y, Courbon GM, Di Trani JM, Wong CJ, Saghian R, Youn JY, Wang LY, Rubinstein JL
Science (2024) [ DOI: doi:10.1126/science.adp5577 ]
- Methyl (3r,6z,10e,14e)-3,7,11,15,19-pentamethylicosa-6,10,14,18-tetraen-1-yl dihydrogen diphosphate (534 Da, Ligand)
- V-type proton atpase subunit s1 (51 kDa, Protein from Rattus norvegicus)
- V-type proton atpase 116 kda subunit a 1 (94 kDa, Protein from Rattus norvegicus)
- Synaptic vesicle v-atpase with synaptophysin and sidk, state 3, vo (Complex from Rattus norvegicus)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- (7r)-4,7-dihydroxy-n,n,n-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacosan-1-aminium 4-oxide (524 Da, Ligand)
- Synaptophysin (33 kDa, Protein from Rattus norvegicus)
- Atpase, h+ transporting, v0 subunit b (predicted), isoform cra_a (21 kDa, Protein from Rattus norvegicus)
- Phosphatidylethanolamine (734 Da, Ligand)
- Rnasek protein (9 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit (40 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit f (13 kDa, Protein from Rattus norvegicus)
- Cholesterol (386 Da, Ligand)
- V-type proton atpase subunit e 2 (9 kDa, Protein from Rattus norvegicus)
- V-type proton atpase 16 kda proteolipid subunit c (15 kDa, Protein from Rattus norvegicus)
- Renin receptor (39 kDa, Protein from Rattus norvegicus)
- Atpase h+-transporting v1 subunit d (28 kDa, Protein from Rattus norvegicus)
Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 3, peripheral stalks
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 9b8q
Q-score: 0.363
Coupland CE, Karimi R, Bueler SA, Liang Y, Courbon GM, Di Trani JM, Wong CJ, Saghian R, Youn JY, Wang LY, Rubinstein JL
Science (2024) [ DOI: doi:10.1126/science.adp5577 ]
- V-type proton atpase subunit c 1 (43 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit h (55 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit g (13 kDa, Protein from Rattus norvegicus)
- V-type proton atpase 116 kda subunit a isoform 1 (96 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Rattus norvegicus)
- Synaptic vesicle v-atpase with synaptophysin and sidk, state 3, peripheral stalks (Complex from Rattus norvegicus)
Yeast VO in complex with Vma12-22p
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8eas
Q-score: 0.606
Wang H, Bueler SA, Rubinstein JL
PNAS (2023) 120 pp. e2217181120-e2217181120 [ DOI: doi:10.1073/pnas.2217181120 Pubmed: 36724250 ]
- V-type proton atpase subunit e (8 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase assembly factor vma12p (16 kDa, Protein from Saccharomyces cerevisiae)
- Yeast v-atpase subunit f (9 kDa, Protein from Saccharomyces cerevisiae)
- V0 assembly protein 1 (29 kDa, Protein from Saccharomyces cerevisiae)
- Yeast vo in complex with vma12-22p (Complex from Saccharomyces cerevisiae)
- V-type proton atpase subunit c'' (22 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit a, vacuolar isoform (95 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit d (39 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c' (17 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit f (13 kDa, Protein from Saccharomyces cerevisiae)
- Vacuolar atpase assembly protein vma22 (21 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c (16 kDa, Protein from Saccharomyces cerevisiae)
Yeast VO missing subunits a, e, and f in complex with Vma12-22p
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8eat
Q-score: 0.529
Wang H, Bueler SA, Rubinstein JL
PNAS (2023) 120 pp. e2217181120-e2217181120 [ Pubmed: 36724250 DOI: doi:10.1073/pnas.2217181120 ]
- V-type proton atpase subunit f (13 kDa, Protein from Saccharomyces cerevisiae)
- V0 assembly protein 1 (29 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c'' (22 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c (16 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c' (17 kDa, Protein from Saccharomyces cerevisiae)
- Vacuolar atpase assembly protein vma22 (21 kDa, Protein from Saccharomyces cerevisiae)
- Vacuolar atpase assembly integral membrane protein vph2 (25 kDa, Protein from Saccharomyces cerevisiae)
- Yeast vo missing subunits a, e, and f in complex with vma12-22p (Complex from Saccharomyces cerevisiae)
- V-type proton atpase subunit d (39 kDa, Protein from Saccharomyces cerevisiae)
Yeast VO in complex with Vma21p
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8eau
Q-score: 0.518
Wang H, Bueler SA, Rubinstein JL
PNAS (2023) 120 pp. e2217181120-e2217181120 [ DOI: doi:10.1073/pnas.2217181120 Pubmed: 36724250 ]
- V-type proton atpase subunit e (8 kDa, Protein from Saccharomyces cerevisiae)
- Yeast v-atpase subunit f (9 kDa, Protein from Saccharomyces cerevisiae)
- Vacuolar atpase assembly integral membrane protein vma21 (8 kDa, Protein from Saccharomyces cerevisiae)
- V0 assembly protein 1 (29 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c'' (22 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit a, vacuolar isoform (95 kDa, Protein from Saccharomyces cerevisiae)
- Yeast vo in complex with vma21p (Complex from Saccharomyces cerevisiae)
- V-type proton atpase subunit c' (17 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit d (39 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c (16 kDa, Protein from Saccharomyces cerevisiae)
YAR027W and YAR028W in complex with c subunits from yeast VO complex
Resolution: 5.7 Å
EM Method: Single-particle
Fitted PDBs: 8eav
Q-score: 0.267
Wang H, Bueler SA, Rubinstein JL
PNAS (2023) 120 pp. e2217181120-e2217181120 [ Pubmed: 36724250 DOI: doi:10.1073/pnas.2217181120 ]
- Yar027w or yar028w (14 kDa, Protein from baker's yeast)
- Subunit from the c ring of yeast vo complex (13 kDa, Protein from baker's yeast)
- Yar027w or yar028w (15 kDa, Protein from baker's yeast)
- Yar027w or yar028w (14 kDa, Protein from baker's yeast)
- Yar027w or yar028w (15 kDa, Protein from baker's yeast)
- Yar027w or yar028w (13 kDa, Protein from baker's yeast)
- Yar027w or yar028w (13 kDa, Protein from baker's yeast)
- Yar027w and yar028w in complex with c subunits from yeast vo complex (Complex from Saccharomyces cerevisiae)
- Yar027w or yar028w (11 kDa, Protein from baker's yeast)
- Yar027w or yar028w (15 kDa, Protein from baker's yeast)
- Yar027w or yar028w (11 kDa, Protein from baker's yeast)
- Subunit from the c ring of yeast vo complex (12 kDa, Protein from baker's yeast)
Yeast VO in complex with Vma12-22p purified via Vma21p-3xFLAG
Wang H, Bueler SA, Rubinstein JL
PNAS (2023) 120 pp. e2217181120-e2217181120 [ Pubmed: 36724250 DOI: doi:10.1073/pnas.2217181120 ]
- V-type proton atpase assembly factor vma22p (Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c' (Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit a (Protein from Saccharomyces cerevisiae)
- Yeast vo in complex with vma12-22p purified via vma21p-3xflag (Complex from Saccharomyces cerevisiae)
- V-type proton atpase subunit e (Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c'' (Protein from Saccharomyces cerevisiae)
- V-type proton atpase voa1p (Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit f (Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit f (Protein from Saccharomyces cerevisiae)
- V-type proton atpase assembly factor vma12p (Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit d (Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit c (Protein from Saccharomyces cerevisiae)