Structure of mouse SCMC bound with KH domain of FILIA
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8h94
Q-score: 0.53
Chi P, Ou G, Qin D, Han Z, Li J, Xiao Q, Gao Z, Xu C, Qi Q, Liu Q, Liu S, Li J, Guo L, Lu Y, Chen J, Wang X, Shi H, Li L, Deng D
Nat Struct Mol Biol (2024) 31 pp. 115-124 [ DOI: doi:10.1038/s41594-023-01153-x Pubmed: 38177687 ]
- Transducin-like enhancer protein 6 (65 kDa, Protein from Mus musculus)
- Nacht, lrr and pyd domains-containing protein 5 (119 kDa, Protein from Mus musculus)
- Mouse scmc bound with kh domain of filia (Complex from Mus musculus)
- Oocyte-expressed protein homolog (18 kDa, Protein from Mus musculus)
Structure of mouse SCMC bound with full-length FILIA
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 8h95
Q-score: 0.445
Chi P, Ou G, Qin D, Han Z, Li J, Xiao Q, Gao Z, Xu C, Qi Q, Liu Q, Liu S, Li J, Guo L, Lu Y, Chen J, Wang X, Shi H, Li L, Deng D
Nat Struct Mol Biol (2024) 31 pp. 115-124 [ DOI: doi:10.1038/s41594-023-01153-x Pubmed: 38177687 ]
- Transducin-like enhancer protein 6 (65 kDa, Protein from Mus musculus)
- Nacht, lrr and pyd domains-containing protein 5 (119 kDa, Protein from Mus musculus)
- Structure of mouse scmc bound with full-length filia (Complex from Mus musculus)
- Oocyte-expressed protein homolog (18 kDa, Protein from Mus musculus)
Structure of mouse SCMC core complex
Resolution: 2.78 Å
EM Method: Single-particle
Fitted PDBs: 8h96
Q-score: 0.546
Chi P, Ou G, Qin D, Han Z, Li J, Xiao Q, Gao Z, Xu C, Qi Q, Liu Q, Liu S, Li J, Guo L, Lu Y, Chen J, Wang X, Shi H, Li L, Deng D
Nat Struct Mol Biol (2024) 31 pp. 115-124 [ DOI: doi:10.1038/s41594-023-01153-x Pubmed: 38177687 ]
- Transducin-like enhancer protein 6 (65 kDa, Protein from Mus musculus)
- Nacht, lrr and pyd domains-containing protein 5 (119 kDa, Protein from Mus musculus)
- Mouse scmc core complex (Complex from Mus musculus)
- Oocyte-expressed protein homolog (18 kDa, Protein from Mus musculus)
CryoEM structure of Nav1.7 VSD2 (actived state) in complex with the gating modifier toxin ProTx2
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6n4q
Q-score: 0.343
Xu H, Li T, Rohou A, Arthur CP, Tzakoniati F, Wong E, Estevez A, Kugel C, Franke Y, Chen J, Ciferri C, Hackos DH, Koth CM, Payandeh J
Cell (2019) 176 pp. 702- [ Pubmed: 30661758 DOI: doi:10.1016/j.cell.2018.12.018 ]
- Beta/omega-theraphotoxin-tp2a (3 kDa, Protein from Thrixopelma pruriens)
- Nav1.7 vsd2 in complex with protx2 and an anti-nav fab (245 kDa, Complex from Homo sapiens)
- Fab light chain (23 kDa, Protein from mouse)
- Nav1.7 vsd2-navab chimera (33 kDa, Protein from Arcobacter butzleri (strain RM4018))
- Fab heavy chain (24 kDa, Protein from Mus musculus)
CryoEM structure of Nav1.7 VSD2 (deactived state) in complex with the gating modifier toxin ProTx2
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6n4r
Q-score: 0.345
Xu H, Li T, Rohou A, Arthur CP, Tzakoniati F, Wong E, Estevez A, Kugel C, Franke Y, Chen J, Ciferri C, Hackos DH, Koth CM, Payandeh J
Cell (2019) 176 pp. 702- [ DOI: doi:10.1016/j.cell.2018.12.018 Pubmed: 30661758 ]
- Nav1.7 vsd2 in complex with protx2 and an anti-nav fab (245 kDa, Complex from Homo sapiens)
- Fab light chain (23 kDa, Protein from mouse)
- Fab heavy chain (24 kDa, Protein from mouse)
- Nav1.7 vsd2-navab chimera (33 kDa, Protein from Arcobacter butzleri (strain RM4018))
- Beta/omega-theraphotoxin-tp2a (3 kDa, Protein from Thrixopelma pruriens)