Electron Microscopy Data Bank

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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primary_citation_author:"Chen J" AND author_name:"Sun H" AND author_name:"He M" AND sample_type:"ligand" AND xref_links:"uniprot"

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EMD-33831

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Cryo-EM structure of the HA trimer of A/Beijing/262/1995(H1N1) in complex with neutralizing antibody 12H5

Release date: Aug. 17, 2022
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 7yhk
Q-score: 0.556

Li T, Chen J, Zheng Q, Xue W, Zhang L, Rong R, Zhang S, Wang Q, Hong M, Zhang Y, Cui L, He M, Lu Z, Zhang Z, Chi X, Li J, Huang Y, Wang H, Tang J, Ying D, Zhou L, Wang Y, Yu H, Zhang J, Gu Y, Chen Y, Li S, Xia N

Nat Commun (2022) 13 pp. 5182-5182 [ DOI: doi:10.1038/s41467-022-32926-5 Pubmed: 36056024 ]

Sample:

2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Ha trimer of a/beijing/262/1995(h1n1) (Complex from Influenza A virus (A/Beijing/262/1995(H1N1)))
12h5 light chain (12 kDa, Protein from Mus musculus)
Cryo-em structure of the ha trimer of a/beijing/262/1995(h1n1) in complex with neutralizing antibody 12h5 (Complex)
Neutralizing antibody 12h5 (Complex from Mus musculus)
12h5 heavy chain (12 kDa, Protein from Mus musculus)
Hemagglutinin (62 kDa, Protein from Influenza A virus (A/Beijing/262/1995(H1N1)))

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