SARS-CoV-2 Omicron spike in complex with 5817 Fab
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8khc
Q-score: 0.351
Wang Y, Zhang Z, Yang M, Xiong X, Yan Q, Cao L, Wei P, Zhang Y, Zhang L, Lv K, Chen J, Liu X, Zhao X, Xiao J, Zhang S, Zhu A, Gan M, Zhang J, Cai R, Zhuo J, Zhang Y, Rao H, Qu B, Zhang Y, Chen L, Dai J, Cheng L, Hu Q, Chen Y, Lv H, So RTY, Peiris M, Zhao J, Liu X, Mok CKP, Wang X, Zhao J
Cell Rep (2024) 43 pp. 113653-113653 [ Pubmed: 38175758 DOI: doi:10.1016/j.celrep.2023.113653 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of 5817 fab (11 kDa, Protein from Homo sapiens)
- Heavy chain of 5817 fab (13 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Spike glycoprotein (124 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron spike in complex with 5817 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
The interface structure of Omicron RBD binding to 5817 Fab
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8khd
Q-score: 0.393
Wang Y, Zhang Z, Yang M, Xiong X, Yan Q, Cao L, Wei P, Zhang Y, Zhang L, Lv K, Chen J, Liu X, Zhao X, Xiao J, Zhang S, Zhu A, Gan M, Zhang J, Cai R, Zhuo J, Zhang Y, Rao H, Qu B, Zhang Y, Chen L, Dai J, Cheng L, Hu Q, Chen Y, Lv H, So RTY, Peiris M, Zhao J, Liu X, Mok CKP, Wang X, Zhao J
Cell Rep (2024) 43 pp. 113653-113653 [ Pubmed: 38175758 DOI: doi:10.1016/j.celrep.2023.113653 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- The interface structure of omicron rbd binding to 5817 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of 5817 (11 kDa, Protein from Homo sapiens)
- Heavy chain of 5817 (13 kDa, Protein from Homo sapiens)
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 7yhk
Q-score: 0.556
Li T, Chen J, Zheng Q, Xue W, Zhang L, Rong R, Zhang S, Wang Q, Hong M, Zhang Y, Cui L, He M, Lu Z, Zhang Z, Chi X, Li J, Huang Y, Wang H, Tang J, Ying D, Zhou L, Wang Y, Yu H, Zhang J, Gu Y, Chen Y, Li S, Xia N
Nat Commun (2022) 13 pp. 5182-5182 [ DOI: doi:10.1038/s41467-022-32926-5 Pubmed: 36056024 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ha trimer of a/beijing/262/1995(h1n1) (Complex from Influenza A virus (A/Beijing/262/1995(H1N1)))
- 12h5 light chain (12 kDa, Protein from Mus musculus)
- Cryo-em structure of the ha trimer of a/beijing/262/1995(h1n1) in complex with neutralizing antibody 12h5 (Complex)
- Neutralizing antibody 12h5 (Complex from Mus musculus)
- 12h5 heavy chain (12 kDa, Protein from Mus musculus)
- Hemagglutinin (62 kDa, Protein from Influenza A virus (A/Beijing/262/1995(H1N1)))
S protein of SARS-CoV-2 in complex with GW01
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7epx
Q-score: 0.347
Wang Y, Liu M, Shen Y, Ma Y, Li X, Zhang Y, Liu M, Yang XL, Chen J, Yan R, Luan D, Wang Y, Chen Y, Wang Q, Lin H, Li Y, Wu K, Zhu T, Zhao J, Lu H, Wen Y, Jiang S, Wu F, Zhou Q, Shi ZL, Huang J
Cell Discov (2022) 8 pp. 36-36 [ DOI: doi:10.1038/s41421-022-00401-6 Pubmed: 35443747 ]
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- S protein of sars-cov-2 in complex with gw01 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of gw01 (22 kDa, Protein from Homo sapiens)
- Fab gw01 (Complex)
- Heavy chain of gw01 (49 kDa, Protein from Homo sapiens)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
Local map of S protein of SARS-CoV-2 in complex with GW01 Focused on RND-GW01 sub_complex